Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394613 | 0.93 | SCN9A (0.43) | THRATHRBFFAR4FFAR1MGLL | |
| SCHEMBL2351022 | 0.89 | MGLL (0.45) | THRATHRBFFAR4FFAR1MGLL | |
| SCHEMBL6063960 | 0.80 | THRA (0.50) | THRATHRBFFAR4RXRARXRB | |
| SCHEMBL6062633 | 0.79 | THRA (0.59) | THRATHRBFFAR4FFAR1 | |
| SCHEMBL6063195 | 0.79 | THRA (0.52) | THRATHRBFFAR4RXRARXRB | |
| SCHEMBL2349128 | 0.77 | THRA (0.55) | THRATHRBFFAR4FFAR1 | |
| SCHEMBL6064208 | 0.77 | THRA (0.75) | THRATHRBFFAR4FFAR1 | |
| SCHEMBL2351164 | 0.76 | FFAR1 (0.70) | THRATHRBFFAR4FFAR1 | |
| SCHEMBL6063323 | 0.75 | FFAR4 (0.52) | THRATHRBFFAR4FFAR1 | |
| SCHEMBL6063119 | 0.74 | FFAR4 (0.67) | THRATHRBFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688138-A1 | RECEPTOR FUNCTION REGULATING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2006-08-09 | — | — | EP | disclosed |