SCHEMBL6064181

SCHEMBL6064181

CC(=COCC(O)CO)C(=O)OC(=O)O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
DUSP3 P51452 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.32
DGKA P23743 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26964423 0.87 KDM4E (0.32) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL27943440 0.85 KDM4E (0.37) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL27310931 0.84 TSHR (0.36) KDM4EDUSP3MEN1KMT2ALMNA
Bicarbonate SCHEMBL28531648 0.83 TGFBR1 (0.35) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL1774307 0.83 LMNA (0.33) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL28008059 0.83 KDM4E (0.40) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL8624307 0.83
SCHEMBL7112947 0.83 TSHR (0.35)
SCHEMBL221966 0.82 KDM4E (0.35) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL29055451 0.80 KDM4E (0.35) KDM4EDUSP3MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7045579-B2 Coating composition comprising an acetal-functional binder AKZO NOBEL N.V. (NL) 2006-05-16 US disclosed
EP-1481029-A1 COATING COMPOSITION COMPRISING AN ACETAL-FUNCTIONAL BINDER Akzo Nobel Coatings International B.V. (NL) 2004-12-01 EP disclosed
US-20030207104-A1 Coating composition comprising an acetal-functional binder AKZO NOBEL N.V. (NL) 2003-11-06 US disclosed
WO-2003074620-A1 COATING COMPOSITION COMPRISING AN ACETAL-FUNCTIONAL BINDER AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2003-09-12 WO disclosed
EP-0337926-A2 Storage stable aqueous emulsions DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-10-18 EP disclosed