SCHEMBL1774307

SCHEMBL1774307

COC(=O)C(C)=COCC(O)CO

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TGFBR1 P36897 1/20 0.33
DGKA P23743 1/20 0.32
AGTR1 P30556 1/20 0.31
CYP1A2 P05177 1/20 0.31
FAAH O00519 2/20 0.31
ALDH1A1 P00352 1/20 0.30
USP2 O75604 1/20 0.30
PLA2G2C Q5R387 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL28531648 0.97 TGFBR1 (0.35) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL28008059 0.86 KDM4E (0.40) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL29055451 0.83 KDM4E (0.35) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL26964423 0.83 KDM4E (0.32) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL27484209 0.83 LMNA (0.38) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL6064181 0.83 KDM4E (0.32) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL221966 0.81 KDM4E (0.35) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL28139213 0.81 KDM4E (0.34) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL28284777 0.81 KDM4E (0.34) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL27943440 0.81 KDM4E (0.37) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240425742-A1 High Temperature Suspension Additive For Wellbore Treatments HALLIBURTON ENERGY SERVICES, INC. (US) 2024-12-26 US claimed
CN-115605529-B Photochromic polydiorganosiloxane vinyl cross-linking agent 爱尔康公司 2024-03-26 CN claimed
CN-111919141-B Silicone Hydrogel Contact Lenses 爱尔康公司 2023-11-14 CN claimed
CN-109690360-B Method for producing contact lenses having durable lubricious coatings thereon 爱尔康公司 2023-04-25 CN claimed
CN-115698776-A Insert material with high oxygen permeability coefficient and high refractive index 爱尔康公司 2023-02-03 CN claimed
CN-115605529-A Photochromic polydiorganosiloxane ethylene crosslinkers 爱尔康公司(CH) 2023-01-13 CN claimed
CN-115298573-A High refractive index silicone insert materials for embedded contact lenses 爱尔康公司 2022-11-04 CN claimed
CN-110709731-B Silicone hydrogel contact lenses 爱尔康公司 2022-05-24 CN claimed
US-20220059846-A1 BATTERY WITH HALOGEN SEQUESTERING AGENT GELION TECHNOLOGIES PTY LTD (AU) 2022-02-24 US claimed
CN-110621483-B Silicone hydrogel contact lenses 爱尔康公司 2021-10-29 CN claimed
CN-110183973-A A kind of solar battery imbrication component conducting resinl and preparation method thereof 苏州柏特瑞新材料有限公司 2019-08-30 CN claimed
US-20160220503-A1 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF ETH ZURICH (CH) 2016-08-04 US claimed
US-20140186445-A1 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF ETH ZURICH (CH) 2014-07-03 US claimed
EP-2709601-A1 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF ETH Zurich (CH) 2014-03-26 EP claimed
CN-103507282-A Method for manufacturing contact lens and contact lens CHIANG KUO-CHING 2014-01-15 CN claimed
WO-2012156065-A1 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF ETH ZURICH (CH) 2012-11-22 WO claimed
EP-2524690-A1 Method for making customised nanoparticles, nanoparticles and use thereof ETH Zurich (CH) 2012-11-21 EP claimed
US-20090200692-A1 Method for manufacturing a silicone contact lens having a hydrophilic surface CHANG JAME 2009-08-13 US claimed
EP-1468033-A1 PHOSPHORUS-CONTAINING URETHANE (METH)ACRYLATE COMPOUNDS AND PHOTOSENSITIVE COMPOSITIONS Showa Denko K.K. (JP) 2004-10-20 EP claimed
WO-2003062296-A1 PHOSPHORUS-CONTAINING URETHANE (METH)ACRYLATE COMPOUNDS AND PHOTOSENSITIVE COMPOSITIONS SHOWA DENKO K. K. (JP) 2003-07-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140186445-A1 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF MSN, CD14, SAMM50 LMNA 790/4885KDM4E 3672/4885DUSP3 3348/4885
US-20160220503-A1 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF MSN, CD14, SAMM50 LMNA 790/4885KDM4E 3672/4885DUSP3 3348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.