Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561234 | 0.82 | GABRA1 (0.45) | GABRA1GABRB2CYP3A4GRIN2DGRIN3B | |
| SCHEMBL93290 | 0.80 | GABRA1 (0.61) | GABRA1GABRB2CYP3A4GRIN2DGRIN3B | |
| SCHEMBL29795971 | 0.80 | GABRA1 (0.61) | GABRA1GABRB2CYP3A4GRIN2DGRIN3B | |
| SCHEMBL11865662 | 0.79 | CYP3A4 (0.48) | GABRA1GABRB2CYP3A4 | |
| SCHEMBL29404189 | 0.78 | CYP3A4 (0.50) | GABRA1GABRB2CYP3A4 | |
| SCHEMBL15544 | 0.78 | CYP3A4 (0.50) | GABRA1GABRB2CYP3A4 | |
| SCHEMBL18701450 | 0.78 | CYP3A4 (0.50) | GABRA1GABRB2CYP3A4 | |
| SCHEMBL23721618 | 0.77 | GABRA1 (0.58) | GABRA1GABRB2CYP3A4 | |
| SCHEMBL1396461 | 0.77 | GABRA1 (0.58) | GABRA1GABRB2CYP3A4 | |
| SCHEMBL17504402 | 0.77 | GABRA1 (0.58) | GABRA1GABRB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4511077-A1 | BONE REPAIR COMPOSITIONS COMPRISING POLYTHIOURETHANE AND USES THEREOF | Smith&Nephew, Inc. (US) | 2025-02-26 | — | — | EP | claimed |
| WO-2023205141-A1 | BONE REPAIR COMPOSITIONS COMPRISING POLYTHIOURETHANE AND USES THEREOF | SMITH & NEPHEW, INC. (US) | 2023-10-26 | — | — | WO | claimed |
| US-9084827-B2 | Biodegradable polyurethane/urea compositions | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2015-07-21 | — | — | US | claimed |
| US-20140099277-A1 | BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2014-04-10 | — | — | US | claimed |
| US-20130150964-A1 | BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2013-06-13 | — | — | US | claimed |
| US-20250262347-A1 | BONE REPAIR COMPOSITIONS COMPRISING POLYTHIOURETHANE AND USES THEREOF | SMITH & NEPHEW INC (US) | 2025-08-21 | — | — | US | disclosed |
| EP-4511077-A1 | BONE REPAIR COMPOSITIONS COMPRISING POLYTHIOURETHANE AND USES THEREOF | Smith&Nephew, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023205141-A1 | BONE REPAIR COMPOSITIONS COMPRISING POLYTHIOURETHANE AND USES THEREOF | SMITH & NEPHEW, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| EP-3042920-A1 | BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS | Polynovo Biomaterials Pty Limited (AU) | 2016-07-13 | — | — | EP | disclosed |
| CN-1774460-B | Biodegradable polyurethane/urea compositions | COMMW SCIENT IND RES ORG | 2010-04-21 | — | — | CN | disclosed |
| CN-1774460-A | Biodegradable polyurethane/urea compositions | COMMW SCIENT IND RES ORG (AU) | 2006-05-17 | — | — | CN | disclosed |
| EP-1572339-A4 | BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS | COMMW SCIENT IND RES ORG (AU) | 2006-04-19 | — | — | EP | disclosed |
| EP-1572339-A2 | BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004009227-A2 | BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140099277-A1 | BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS | PUF60, UMPS, COL2A1 | GABRA1 3692/4885GABRB2 3541/4885CYP3A4 2965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.