Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 4/20 | 0.46 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065108 | 1.00 | FAAH (0.48) | FAAHMAPTKMT2ACES2CES1 | |
| SCHEMBL28755674 | 0.92 | ALDH1A1 (0.51) | MAPTKMT2ABLMHSD17B10FABP4 | |
| SCHEMBL8459576 | 0.84 | FAAH (0.50) | FAAHMAPTKMT2ACES2CES1 | |
| SCHEMBL8459575 | 0.84 | FAAH (0.50) | FAAHMAPTKMT2ACES2CES1 | |
| SCHEMBL11853510 | 0.84 | ALDH1A1 (0.40) | FAAHMAPTKMT2ACES2CES1 | |
| SCHEMBL11853506 | 0.84 | ALDH1A1 (0.40) | FAAHMAPTKMT2ACES2CES1 | |
| SCHEMBL16689754 | 0.84 | ALDH1A1 (0.40) | FAAHMAPTKMT2ACES2CES1 | |
| SCHEMBL6063443 | 0.83 | FAAH (0.70) | FAAHMAPTKMT2ATERTBLM | |
| SCHEMBL6472922 | 0.83 | FAAH (0.70) | FAAHMAPTKMT2ATERTBLM | |
| SCHEMBL8459328 | 0.83 | MAPT (0.54) | FAAHMAPTKMT2ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638913-A1 | PROCESSES FOR PREPARING BETA-HYDROXY-KETONES AND ALPHA, BETA-UNSATURATED KETONES | EASTMAN CHEMICAL COMPANY (US) | 2006-03-29 | — | — | EP | disclosed |
| US-6960694-B2 | Processes for preparing β-hydroxy-ketones and α,β-unsaturated ketones | EASTMAN CHEMICAL COMPANY (US) | 2005-11-01 | — | — | US | disclosed |
| WO-2005005361-A1 | PROCESSES FOR PREPARING BETA-HYDROXY-KETONES AND ALPHA, BETA-UNSATURATED KETONES | EASTMAN CHEMICAL COMPANY (US) | 2005-01-20 | — | — | WO | disclosed |
| US-20050004401-A1 | Processes for preparing beta-hydroxy-ketones and alpha,beta-unsaturated ketones | EASTMAN CHEMICAL COMPANY | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004401-A1 | Processes for preparing beta-hydroxy-ketones and alpha,beta-unsaturated ketones | EBP, CYP8B1, BCKDK | FAAH 101/4885MAPT 2012/4885KMT2A 2524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.