Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.65 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11183801 | 0.81 | CES1 (0.58) | SRCCES1TSHRMAPTMAPK1 | |
| SCHEMBL8675207 | 0.80 | PIN1 (0.50) | SRCCES1TSHRMAPTNPC1 | |
| SCHEMBL8655870 | 0.79 | SRC (0.53) | SRCCES1TSHRKCNN4MAPT | |
| SCHEMBL8655862 | 0.79 | KMT2A (0.52) | SRCCES1TSHRKCNN4ELANE | |
| SCHEMBL9558390 | 0.78 | SRC (0.67) | SRCCES1TSHRKCNN4ELANE | |
| SCHEMBL28899222 | 0.78 | SRC (1.00) | SRCCES1TSHRKCNN4ELANE | |
| SCHEMBL27722489 | 0.78 | SRC (0.72) | SRCCES1TSHRKCNN4ELANE | |
| SCHEMBL8674719 | 0.77 | CES1 (0.54) | SRCCES1TSHRMAPTMAPK1 | |
| SCHEMBL11491527 | 0.77 | SRC (0.65) | SRCCES1TSHRKCNN4ELANE | |
| SCHEMBL12083381 | 0.77 | SRC (0.70) | SRCCES1TSHRKCNN4ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084281-B2 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-08-01 | — | — | US | disclosed |
| US-20040143125-A1 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2004-07-22 | — | — | US | disclosed |
| EP-0519140-B1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acids, esters and salts thereof, and intermediates used in this method | HYBRINOVA (FR) | 1998-07-29 | — | — | EP | disclosed |
| US-5304672-A | Intermediates for pollen suppressants | ORSAN (FR) | 1994-04-19 | — | — | US | disclosed |
| US-5183891-A | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | ORSAN (FR) | 1993-02-02 | — | — | US | disclosed |
| EP-0519140-A1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | HYBRINOVA (FR) | 1992-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143125-A1 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins | TALDO1, HDHD5, TKT | SRC 3482/4885CES1 318/4885TSHR 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.