SCHEMBL6065230

SCHEMBL6065230

C=CCOC(=O)C=C1C=C(C(C)(C)C)C(=O)C(C(C)(C)C)=C1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.36
NPC1 O15118 1/20 0.36
KMT2A Q03164 1/20 0.36
GPR35 Q9HC97 1/20 0.36
CYP3A4 P08684 1/20 0.35
APP P05067 1/20 0.34
MAPT P10636 2/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
NPSR1 Q6W5P4 2/20 0.32
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
HSD17B10 Q99714 1/20 0.31
CES2 O00748 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
CES1 P23141 1/20 0.31
MPI P34949 1/20 0.31
RHOA P61586 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL85767 0.78 ATM (0.44) ATMNPC1KMT2AGPR35MAPT
SCHEMBL8675243 0.73 ATM (0.39) ATMNPC1KMT2AGPR35MAPT
SCHEMBL22930710 0.66 ATM (0.44) ATMNPC1KMT2AGPR35MAPT
SCHEMBL6249541 0.65 ATM (0.38) ATMNPC1KMT2AGPR35MAPT
SCHEMBL20875962 0.65 ATM (0.41) ATMNPC1KMT2AGPR35MAPT
Chloromethane SCHEMBL28424741 0.64 TSHR (0.50) KMT2ACYP3A4APPMAPTCACNA1B
SCHEMBL85970 0.63 ATM (0.49) ATMNPC1KMT2AGPR35MAPT
SCHEMBL85988 0.63 ATM (0.42) ATMNPC1KMT2AGPR35MAPT
SCHEMBL7356306 0.62
SCHEMBL24790849 0.62 ATM (0.38) ATMNPC1KMT2AGPR35MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7045647-B2 Blends of quinone alkide and nitroxyl compounds and polymerization inhibitors UNIROYAL CHEMICAL COMPANY, INC. (US) 2006-05-16 US claimed