SCHEMBL6065573

SCHEMBL6065573

Oc1cccc2ccc(Br)nc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 2/20 0.59
PLAU P00749 1/20 0.59
NCF1 P14598 1/20 0.59
ALOX12 P18054 3/20 0.57
ALDH1A1 P00352 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2C9 P11712 1/20 0.57
HPGD P15428 1/20 0.57
CYP2C19 P33261 1/20 0.57
HIF1A Q16665 1/20 0.57
HSD17B10 Q99714 1/20 0.57
KMT2A Q03164 6/20 0.53
KDM4E B2RXH2 5/20 0.53
SOS2 Q07890 1/20 0.53
TSHR P16473 2/20 0.52
MMP2 P08253 1/20 0.52
CHRM1 P11229 1/20 0.52
COMT P21964 1/20 0.52
ADRA1A P35348 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339928 0.77 BACE1 (0.63) METAP2PLAUNCF1ALDH1A1CYP1A2
SCHEMBL672744 0.77 METAP2 (0.63) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL21767732 0.77 METAP2 (0.63) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL30082244 0.77 METAP2 (0.63) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL30657716 0.77 BACE1 (0.63) METAP2PLAUNCF1ALDH1A1CYP1A2
SCHEMBL1496246 0.76 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL15442576 0.76 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
Ammonia Solution, Strong SCHEMBL3284067 0.76 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL16444064 0.76 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL6540982 0.76 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105828657-B Utensil for shaping fibrous material 宝洁公司 2019-07-16 CN claimed
CN-105828793-B Shaping keratin fibres using sugar 宝洁公司 2019-06-18 CN claimed
CN-105873563-A Methods for shaping fibrous material and treatment compositions therefor 宝洁公司 2016-08-17 CN claimed
CN-105828788-A Methods for shaping fibrous material and treatment compositions therefor 宝洁公司 2016-08-03 CN claimed
CN-105828786-A Shaping keratin fibres using AN AN active agent comprising a functional group selected from-C (═ O) -, -C (═ O) -H and-C (═ O) -O-) 宝洁公司 2016-08-03 CN claimed
CN-105828794-A METHODS FOR SHAPING FIBROUS MATERIAL AND TREATMENT COMPOSITIONS THEREFOR 宝洁公司 2016-08-03 CN claimed
CN-105828787-A Shaping keratin fibres using oxoacetic acids and/or derivatives thereof 宝洁公司 2016-08-03 CN claimed
CN-105828879-A Method for shaping fibrous material and treatment compositions therefor 宝洁公司 2016-08-03 CN claimed
CN-105828799-A Method for shaping fibrous material and treatment composition therefor 宝洁公司 2016-08-03 CN claimed
CN-105828793-A Shaping keratin fibres using sugar 宝洁公司 2016-08-03 CN claimed
CN-105828791-A Shaping keratin fibres using carbonate ester 宝洁公司 2016-08-03 CN claimed
CN-101611009-A Quinoline derivatives CHRONOGEN INC (US) 2009-12-23 CN claimed
WO-2006117660-A2 METHOD FOR TREATING CANCER, CORONARY, INFLAMMATORY AND MACULAR DISEASE, COMBINING THE MODULATION OF ZINC- AND/OR COPPER DEPENDENT PROTEINS CLIO PHARMACEUTICAL CORPORATION (US) 2006-11-09 WO claimed
US-11889750-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-01-30 US disclosed
CN-117209425-A Synthetic method of polyhalogenated quinoline compound 武威广达科技有限公司 2023-12-12 CN disclosed
CN-108947898-B Organic photoelectric functional material and application thereof 南京工业大学 2021-11-05 CN disclosed
CN-101159319-A Organic el element TOYOTA IND CORP (JP) 2008-04-09 CN disclosed
CN-1681791-A 8-hydroxy quinoline derivatives PRANA BIOTECHNOLOGY LTD (AU) 2005-10-12 CN disclosed
CN-1604704-A Organic electroluminescent device TOYODA AUTOMATIC LOOM WORKS (JP) 2005-04-06 CN disclosed
CN-1505450-A Organic electroluminescent device ��ʽ��������Զ�֯�������� 2004-06-16 CN disclosed