Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3119092 | 0.89 | LPAR1 (0.38) | LPAR1NTRK1BRD4BRD9KAT2B | |
| SCHEMBL6425412 | 0.88 | ALDH1A1 (0.37) | LPAR1NTRK1BRD4BRD9KAT2B | |
| SCHEMBL6065837 | 0.88 | LPAR1 (0.37) | LPAR1NTRK1BRD4BRD9KAT2B | |
| SCHEMBL3111828 | 0.85 | NTRK1 (0.36) | LPAR1NTRK1BRD4BRD9KAT2B | |
| SCHEMBL5500962 | 0.85 | ADRA2C (0.39) | LPAR1NTRK1BRD4BRD9KAT2B | |
| SCHEMBL6425423 | 0.85 | HPGD (0.40) | NTRK1MEN1KMT2AHTTMAPK1 | |
| SCHEMBL5497720 | 0.83 | KDM4E (0.36) | LPAR1NTRK1BRD4BRD9KAT2B | |
| SCHEMBL3105963 | 0.83 | ALDH1A1 (0.41) | LPAR1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL4199230 | 0.81 | BRD9 (0.36) | LPAR1BRD4BRD9KAT2BBPTF | |
| SCHEMBL6385917 | 0.81 | NTRK1 (0.36) | LPAR1NTRK1BRD4BRD9KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663245-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005027909-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2005-03-31 | — | — | WO | disclosed |