SCHEMBL6066038

Cc1cn([C@H]2C[C@H](OP(O)O[N+](CCC#N)(C(C)C)C(C)C)[C@@H]([C@@H](O)C(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]c1=O

nearest known ligand 0.43

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	RNASE1	P07998	1/20	0.42

▸	TK1	P04183	5/20	0.39

▸	TK2	O00142	1/20	0.36

▸	NT5M	Q9NPB1	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6066074	0.86	RNASE1 (0.43)	RNASE1TK1TK2
SCHEMBL439033	0.77	RNASE1 (0.39)	RNASE1TK1TK2
SCHEMBL8598213	0.75	RNASE1 (0.45)	RNASE1TK1NT5M
SCHEMBL8389715	0.75	RNASE1 (0.41)	RNASE1TK1TK2NT5M
SCHEMBL4626081	0.75	TK1 (0.55)	TK1
SCHEMBL14815673	0.73	RNASE1 (0.43)	RNASE1TK1TK2NT5M
SCHEMBL3625226	0.73	RNASE1 (0.39)	RNASE1TK1TK2
SCHEMBL10802980	0.72	RNASE1 (0.43)	RNASE1TK1NT5M
SCHEMBL11050604	0.71	RNASE1 (0.38)	RNASE1TK1TK2NT5M
SCHEMBL25511815	0.71	RNASE1 (0.38)	RNASE1TK1TK2NT5M

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20060040282-A1	Oligonucleotide sizing using cleavable primers	SEQUENOM, INC. (US)	2006-02-23	—	—	US	disclosed
US-6949633-B1	Primers useful for sizing nucleic acids	SEQUENOM, INC. (US)	2005-09-27	—	—	US	disclosed
EP-0828855-B1	Oligonucleotide sizing using cleavable primers	STANFORD RES INST INT (US)	1999-12-15	—	—	EP	disclosed
US-5830655-A	DETERMINATION THE SIZE OF PRIMER EXTENSION	SRI INTERNATIONAL (US)	1998-11-03	—	—	US	disclosed