SCHEMBL6066074

SCHEMBL6066074

Cc1cn([C@H]2C[C@H](O[P@](O)O[N+](CCC#N)(C(C)C)C(C)C)[C@@H](CSC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]c1=O

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.43
TK1 P04183 5/20 0.38
TK2 O00142 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6066038 0.86 RNASE1 (0.42) RNASE1TK1TK2
SCHEMBL2594574 0.78 RNASE1 (0.39) RNASE1TK1TK2
SCHEMBL6514654 0.77 RNASE1 (0.48) RNASE1TK1
SCHEMBL8658996 0.77 TK1 (0.44) TK1
SCHEMBL2594578 0.75 RNASE1 (0.42) RNASE1TK1TK2
SCHEMBL1883689 0.74 TK1 (0.55) TK1
SCHEMBL1883691 0.74 TK1 (0.55) TK1
SCHEMBL8918376 0.71
SCHEMBL7908347 0.71 TK1 (0.51) TK1
SCHEMBL8654714 0.69 RNASE1 (0.43) RNASE1TK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060040282-A1 Oligonucleotide sizing using cleavable primers SEQUENOM, INC. (US) 2006-02-23 US disclosed
US-6949633-B1 Primers useful for sizing nucleic acids SEQUENOM, INC. (US) 2005-09-27 US disclosed
EP-0828855-B1 Oligonucleotide sizing using cleavable primers STANFORD RES INST INT (US) 1999-12-15 EP disclosed
US-5830655-A DETERMINATION THE SIZE OF PRIMER EXTENSION SRI INTERNATIONAL (US) 1998-11-03 US disclosed
EP-0828855-A1 OLIGONUCLEOTIDE SIZING USING CLEAVABLE PRIMERS SRI INTERNATIONAL (US) 1998-03-18 EP disclosed
US-5700642-A HYBRIDIZING PRIMER WITH COMPLEMENTARY TARGET NUCLEIC ACID, ENZYMATICALLY EXTENDING PRIMER TO GENERATE POLYNUCLEOTIDE MIXTURE, IMMOBILIZATION, CLEAVING TO RELEASE EXTENSION SEGMENT AND MEASUREMENT BY MASS SPECTROMETRY SRI INTERNATIONAL (US) 1997-12-23 US disclosed
WO-1996037630-A1 OLIGONUCLEOTIDE SIZING USING CLEAVABLE PRIMERS SRI INTERNATIONAL (US) 1996-11-28 WO disclosed