TUBA3E

Tubulin alpha-3E chain (EC 3.6.5.-) (Alpha-tu · Q6PEY2 · TUBA3E on Sugi Atlas →

132,887 patent compounds predicted against TUBA3E, 84,095 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Curacin A Curacin A (SCHEMBL61304) 1.00 20/20
Vintriptol Vintriptol (SCHEMBL93959) 1.00 15/20
Vindesine Vindesine (SCHEMBL4420) 0.85 13/20
Vindesine Vindesine (SCHEMBL4421) 0.85 13/20
Vindesine Vindesine (SCHEMBL4285) 0.85 12/20
SCHEMBL147173 SCHEMBL147173 0.50 12/20
SCHEMBL147174 SCHEMBL147174 0.50 12/20
Combretastatin Combretastatin (SCHEMBL19955) 1.00 9/20
Combretastatin Combretastatin (SCHEMBL19956) 1.00 9/20
SCHEMBL118593 SCHEMBL118593 0.69 9/20
Centaureidin Centaureidin (SCHEMBL9953) 1.00 8/20
Thiocolchicine Thiocolchicine (SCHEMBL43160) 1.00 8/20
Thiocolchicine Thiocolchicine (SCHEMBL43161) 1.00 8/20
SCHEMBL68067 SCHEMBL68067 0.62 8/20
Fosbretabulin Fosbretabulin (SCHEMBL66079) 0.61 8/20
Vinorelbine Vinorelbine (SCHEMBL4765) 1.00 7/20
Combretastatin A4 Combretastatin A4 (SCHEMBL18945) 1.00 7/20
Combretastatin A4 Combretastatin A4 (SCHEMBL18946) 1.00 7/20
Levofloxacin Anhydrous Levofloxacin Anhydrous (SCHEMBL15397) 0.98 7/20
Ofloxacin Ofloxacin (SCHEMBL24373) 0.98 7/20

Clinical trials — most relevant to TUBA3E by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Comparative and Efficacy Study of ACTHar Gel Alone or in Combination With Tacrolimus in Fibrillary Glomerulopathy PHASE4WITHDRAWN
Comparative Analysis of the Efficacies in Neoadjuvant Chemotherapy of Breast Cancer PHASE3COMPLETED
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
First-line Gemcitabine Plus Cisplatin in Locally Advanced (IIIC Stage) Breast Cancer Patients PHASE2ACTIVE_NOT_RECRUITING
Biologic Correlative Taxotere/AC PHASE2COMPLETED
A Multicenter Study of NAP (AL-108) in Schizophrenia PHASE2COMPLETED
Vinorelbine in Relapsed Platinum Resistant or Refractory C5 High Grade Serous, Endometrioid, or Undifferentiated Primary Peritoneum, Fallopian Tube or Ovarian Cancer PHASE2UNKNOWN
Neoadjuvant Paclitaxel Plus Epirubicin Versus Vinorelbine Plus Epirubicin in Breast Cancer With TEKT4 Variations PHASE2COMPLETED
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer PHASE2COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies PHASE1COMPLETED
Phase I Study to Assess the Safety, Pharmacokinetics, & Pharmacodynamics of GSK923295 in Subjects w/ Refractory Cancer PHASE1COMPLETED
Exploratory Evaluation of [11C]MPC6827 EARLY_PHASE1COMPLETED
Generating Intervals of Reference FFor Early Life Brain Biomarkers. nanRECRUITING
Diagnostic of Chemotherapy Induced Neuropathy in Children nanCOMPLETED
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting nanUNKNOWN
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
Importance of the Microtubule Cytoskeleton in Oocyte Competence nanCOMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Effect of Low Dose of Colchicine on Platelet Reactivity nanCOMPLETED
PCD New Gene Discovery nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Biomarkers in the Diagnosis and Prognosis of NAFLD nanRECRUITING
Prostate Cancer Antigen 3 (PCA-3) Gene Project nanCOMPLETED
Early Detection and Characterization of Primary Ciliary Dyskinesia nanUNKNOWN
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
The Relation of Microtubule-Associated Protein 2 and Cell Migration nanUNKNOWN
Predicting Postoperative Delirium Using EEG, Genetics and Neurobiomarkers of Cerebral Injury nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a TUBA3E binder may also engage these)

ProteinNameSimilarity
P68369 1.000 P68369 →
P02552 1.000 P02552 →
TUBA4A Tubulin alpha-4A chain 1.000 landscape →
Q32KN8 1.000 Q32KN8 →
Q52PV9 1.000 Q52PV9 →
Q94572 1.000 Q94572 →
P18288 1.000 P18288 →
Q6AYZ1 1.000 Q6AYZ1 →
A5A6J1 1.000 A5A6J1 →
Q68FR8 1.000 Q68FR8 →
P68360 1.000 P68360 →
Q2HJB8 1.000 Q2HJB8 →
P68373 1.000 P68373 →
P05214 1.000 P05214 →
TUBA3C Tubulin alpha-3C chain (EC 3.6.5.-) (Alpha-tu 1.000 landscape →
P68370 1.000 P68370 →
Q06331 1.000 Q06331 →
Q2HJ86 1.000 Q2HJ86 →
Q25008 1.000 Q25008 →
P68361 1.000 P68361 →
Q8T6A5 1.000 Q8T6A5 →
P28287 1.000 P28287 →
Q6AY56 1.000 Q6AY56 →
P34690 1.000 P34690 →
TUBA8 Tubulin alpha-8 chain 1.000 landscape →
Q5R1W4 1.000 Q5R1W4 →
P68367 1.000 P68367 →
P68368 1.000 P68368 →
Q5XIF6 1.000 Q5XIF6 →
Q28IX8 1.000 Q28IX8 →