SCHEMBL6067673

SCHEMBL6067673

C=CCCCC(C)(C(=O)O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
ABCC4 O15439 1/20 0.45
ACLY P53396 1/20 0.41
ALDH1A1 P00352 6/20 0.39
LMNA P02545 2/20 0.39
TSHR P16473 5/20 0.39
L3MBTL1 Q9Y468 1/20 0.34
FFAR1 O14842 1/20 0.32
CPT2 P23786 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
USP2 O75604 2/20 0.32
CYP3A4 P08684 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
RECQL P46063 1/20 0.32
ACACB O00763 1/20 0.31
ACACA Q13085 1/20 0.31
LPAR2 Q9HBW0 1/20 0.31
LPAR3 Q9UBY5 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18420923 0.94 MAPT (0.50) MAPTABCC4ACLYALDH1A1LMNA
SCHEMBL6067605 0.94 MAPT (0.50) MAPTABCC4ACLYALDH1A1LMNA
SCHEMBL8385882 0.88 ACLY (0.38) MAPTABCC4ACLYALDH1A1LMNA
SCHEMBL28677379 0.82 ACLY (0.47) MAPTACLYALDH1A1LMNATSHR
SCHEMBL4904722 0.82 MAPT (0.45) MAPTABCC4ACLYALDH1A1LMNA
SCHEMBL2894770 0.82 ACLY (0.61) MAPTABCC4ACLYALDH1A1LMNA
SCHEMBL5474459 0.80 ALDH1A1 (0.42) ACLYALDH1A1TSHRFFAR1CPT2
SCHEMBL20140628 0.79 CYP4F2 (0.41) MAPTABCC4ACLYALDH1A1LMNA
SCHEMBL13467362 0.79 ACLY (0.41) MAPTABCC4ACLYALDH1A1LMNA
SCHEMBL6059309 0.79 TET2 (0.45) MAPTABCC4ACLYALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006100606-A2 PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION WARNER-LAMBERT COMPANY LLC (US) 2006-09-28 WO claimed
US-10240011-B2 Multifunctional curing agents and their use in improving strength of composites containing carbon fibers embedded in polymeric matrix UT-BATTELLE, LLC (US) 2019-03-26 US disclosed
US-20170166712-A1 MULTIFUNCTIONAL CURING AGENTS AND THEIR USE IN IMPROVING STRENGTH OF COMPOSITES CONTAINING CARBON FIBERS EMBEDDED IN POLYMERIC MATRIX UT-BATTELLE, LLC (US) 2017-06-15 US disclosed
US-9617398-B2 Multifunctional curing agents and their use in improving strength of composites containing carbon fibers embedded in a polymeric matrix UT-BATTELLE, LLC (US) 2017-04-11 US disclosed
US-20160102180-A1 MULTIFUNCTIONAL CURING AGENTS AND THEIR USE IN IMPROVING STRENGTH OF COMPOSITES CONTAINING CARBON FIBERS EMBEDDED IN A POLYMERIC MATRIX UT-BATTELLE, LLC (US) 2016-04-14 US disclosed