Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 9/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 9/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 8/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067974 | 0.85 | PTPN1 (0.67) | DYRK1AFSCN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6067997 | 0.83 | DYRK1A (0.71) | DYRK1AFSCN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2790634 | 0.81 | DYRK1A (0.64) | DYRK1AFSCN1NPC1RAB9ASMN1; SMN2 | |
| Potassium Ion SCHEMBL2790230 | 0.79 | DYRK1A (0.61) | DYRK1AFSCN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27173084 | 0.77 | DYRK1A (0.70) | DYRK1AFSCN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29477209 | 0.77 | DYRK1A (0.70) | DYRK1AFSCN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6068064 | 0.77 | RAB9A (0.58) | DYRK1ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6068055 | 0.75 | RAB9A (0.60) | DYRK1ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6068110 | 0.75 | ABL1 (0.80) | DYRK1AFSCN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2791913 | 0.75 | PTPN1 (0.69) | DYRK1AFSCN1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091227-B2 | Benzothiazole derivatives | ABBOTT GMBH & CO. KG (DE) | 2006-08-15 | — | — | US | disclosed |
| US-20030153568-A1 | Benzothiazole derivatives | BASF AKTIENGESELLSCHAFT LUDWIGSHAFEN, GERMANY | 2003-08-14 | — | — | US | disclosed |
| CN-1422262-A | 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors | ABBOTT GMBH & CO KG (DE) | 2003-06-04 | — | — | CN | disclosed |
| EP-1254123-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | Abbott GmbH & Co. KG (DE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001057008-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | ABBOTT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG & COMPANY KOMMANDITGESELLSCHAFT (DE) | 2001-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153568-A1 | Benzothiazole derivatives | TK1, FLT1, CDK1 | DYRK1A 231/4885FSCN1 4525/4885NPC1 3594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.