Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.72 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | STAT1 | P42224 | 1/20 | 0.65 |
| ▸ | ACP1 | P24666 | 1/20 | 0.65 |
| ▸ | ABL1 | P00519 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.61 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18529293 | 0.84 | MAPT (0.63) | KMT2ADYRK1ACXCR2MAPTSMN1; SMN2 | |
| SCHEMBL3924050 | 0.84 | DYRK1A (1.00) | KMT2ADYRK1ACXCR2MAPTSMN1; SMN2 | |
| SCHEMBL6295875 | 0.83 | CXCR2 (0.79) | KMT2ADYRK1ACXCR2MAPTSMN1; SMN2 | |
| SCHEMBL6068168 | 0.83 | ABL1 (0.71) | KMT2ASMN1; SMN2ABL1NPC1RAB9A | |
| SCHEMBL11161571 | 0.82 | KMT2A (0.73) | KMT2ADYRK1ACXCR2MAPTSMN1; SMN2 | |
| SCHEMBL16732745 | 0.82 | DYRK1A (0.78) | KMT2ADYRK1ACXCR2MAPTSMN1; SMN2 | |
| SCHEMBL10599108 | 0.82 | KMT2A (0.80) | KMT2ADYRK1ACXCR2MAPTSMN1; SMN2 | |
| SCHEMBL16747337 | 0.81 | DYRK1A (0.77) | KMT2ADYRK1ACXCR2MAPTSMN1; SMN2 | |
| SCHEMBL27093075 | 0.81 | CXCR2 (0.72) | KMT2ADYRK1ACXCR2MAPTSMN1; SMN2 | |
| SCHEMBL27566837 | 0.81 | DYRK1A (0.76) | KMT2ADYRK1ACXCR2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091227-B2 | Benzothiazole derivatives | ABBOTT GMBH & CO. KG (DE) | 2006-08-15 | — | — | US | disclosed |
| US-20030153568-A1 | Benzothiazole derivatives | BASF AKTIENGESELLSCHAFT LUDWIGSHAFEN, GERMANY | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153568-A1 | Benzothiazole derivatives | TK1, FLT1, CDK1 | KMT2A 2137/4885DYRK1A 231/4885CXCR2 1307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.