SCHEMBL6068751

SCHEMBL6068751

CC(CS(=O)(=O)O)n1ncc(N)c1N1CCC(O)C1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMPD3 Q9NY59 3/20 0.33
RORC P51449 3/20 0.33
CNR2 P34972 1/20 0.31
LRRK2 Q5S007 1/20 0.31
DPP4 P27487 2/20 0.31
AOC3 Q16853 1/20 0.30
IKBKB O14920 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6068622 0.81 PDPK1 (0.36) SMPD3CNR2LRRK2AOC3
SCHEMBL5424966 0.73 FPR1 (0.30)
SCHEMBL6068366 0.68 SMPD3 (0.39) SMPD3CNR2LRRK2AOC3
Bromide SCHEMBL6068862 0.67 SMPD3 (0.38) SMPD3CNR2LRRK2AOC3
Bromide SCHEMBL6068466 0.67 SMPD3 (0.38) SMPD3CNR2LRRK2AOC3
SCHEMBL6068463 0.67 ELANE (0.34)
SCHEMBL6068593 0.65 SIGMAR1 (0.40) SMPD3
SCHEMBL6068757 0.65 POLB (0.30)
SCHEMBL6068715 0.65 CNR2 (0.38) SMPD3CNR2LRRK2AOC3
SCHEMBL6068852 0.64 PLAU (0.33) SMPD3AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7091350-B2 Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres L'OREAL (FR) 2006-08-15 US disclosed