Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14445198 | 0.78 | KMO (0.37) | KMOMAPT | |
| SCHEMBL6068788 | 0.78 | SMPD3 (0.32) | SMPD3 | |
| SCHEMBL6068886 | 0.74 | KMO (0.35) | KMO | |
| SCHEMBL6068792 | 0.71 | SMPD3 (0.33) | SMPD3 | |
| SCHEMBL6069260 | 0.70 | KMO (0.42) | GAAKMOLNPEPPOLB | |
| SCHEMBL6068966 | 0.66 | SCN9A (0.36) | GAAKMO | |
| SCHEMBL14445241 | 0.66 | KMO (0.49) | KMOMAPTPOLBSMN1; SMN2 | |
| SCHEMBL14838485 | 0.66 | SMPD3 (0.40) | SMPD3SMN1; SMN2 | |
| SCHEMBL6068751 | 0.64 | SMPD3 (0.33) | AOC3SMPD3 | |
| SCHEMBL6068725 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |
| US-20040088802-A1 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040088802-A1 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | CBR3, CBR1, CYB5R3 | PLAU 4661/4885GAA 4450/4885KMO 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.