Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068853 | 0.77 | ELOVL1 (0.39) | SIGMAR1SMPD3HRH3GAA | |
| SCHEMBL6068485 | 0.75 | SRC (0.32) | SMPD3 | |
| SCHEMBL6068639 | 0.74 | HTR1A (0.30) | CNR1 | |
| SCHEMBL1799691 | 0.74 | CNR1 (0.35) | SMPD3CNR2CNR1 | |
| SCHEMBL17610321 | 0.73 | CNR1 (0.34) | SMPD3CNR2CNR1 | |
| SCHEMBL14838485 | 0.72 | SMPD3 (0.40) | SMPD3CNR2 | |
| SCHEMBL6068683 | 0.71 | SLC29A1 (0.32) | SIGMAR1SMPD3 | |
| SCHEMBL6068489 | 0.71 | SMPD3 (0.33) | SIGMAR1SMPD3RAB9A | |
| SCHEMBL6068788 | 0.70 | SMPD3 (0.32) | SMPD3 | |
| SCHEMBL5427359 | 0.69 | CNR1 (0.34) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |
| US-20040088802-A1 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040088802-A1 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | CBR3, CBR1, CYB5R3 | SIGMAR1 13/4885SMPD3 4191/4885HRH3 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.