SCHEMBL606869

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27574238	0.86	ALDH1A1 (0.57)	ALDH1A1RECQLMMP8MEN1KMT2A
	SCHEMBL1835704	0.85	RECQL (0.56)	ALDH1A1RECQLMMP8TAAR1THRB
	SCHEMBL27395266	0.84	ALDH1A1 (1.00)	ALDH1A1RECQLMMP8TAAR1THRB
	SCHEMBL28914937	0.81	ALDH1A1 (0.89)	ALDH1A1RECQLMMP8TAAR1THRB
	SCHEMBL2329888	0.81	ALDH1A1 (0.53)	ALDH1A1RECQLMMP8TAAR1LMNA
	SCHEMBL2331138	0.81	ALDH1A1 (0.53)	ALDH1A1RECQLMMP8TAAR1LMNA
	SCHEMBL8410894	0.81	ALDH1A1 (0.53)	ALDH1A1RECQLMMP8TAAR1LMNA
	SCHEMBL3458059	0.78	ALDH1A1 (0.50)	ALDH1A1RECQLMMP8TAAR1KMT2A
	SCHEMBL8710582	0.78	MMP8 (0.79)	ALDH1A1RECQLMMP8TAAR1THRB
	SCHEMBL1492859	0.78	MMP8 (0.65)	ALDH1A1RECQLMMP8TAAR1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.