Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15651733 | 0.78 | ALDH1A1 (0.35) | MAOAMAOBALDH1A1LMNATDP1 | |
| SCHEMBL7455612 | 0.74 | PDE10A (0.43) | HCAR3MAPK1MAOAMAOBALDH1A1 | |
| SCHEMBL6068848 | 0.73 | MAPK1 (0.36) | HCAR3MAPK1MAOAMAOBALDH1A1 | |
| SCHEMBL6068724 | 0.73 | TDP1 (0.33) | MAOBALDH1A1LMNATDP1 | |
| SCHEMBL6068455 | 0.73 | TDP1 (0.33) | MAOBALDH1A1SMN1; SMN2LMNATDP1 | |
| Dimethylformamide SCHEMBL27912979 | 0.73 | HCAR3 (0.36) | HCAR3MAPK1MAOAMAOBALDH1A1 | |
| SCHEMBL6068924 | 0.72 | TDP1 (0.31) | MAOAMAOBALDH1A1LMNATDP1 | |
| SCHEMBL28805092 | 0.71 | ALDH1A1 (0.39) | HCAR3MAPK1MAOAMAOBALDH1A1 | |
| SCHEMBL6068677 | 0.71 | TDP1 (0.32) | ALDH1A1LMNATDP1 | |
| SCHEMBL6068470 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |