Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068761 | 0.87 | GAA (0.39) | LMNASMN1; SMN2KDM4ES1PR1ALDH1A1 | |
| SCHEMBL6068842 | 0.84 | PDE4A (0.33) | SMN1; SMN2KDM4EMAPK1ALDH1A1 | |
| SCHEMBL6068684 | 0.83 | LMNA (0.36) | LMNASMN1; SMN2KDM4EMAPK1S1PR1 | |
| SCHEMBL6068547 | 0.83 | LMNA (0.31) | LMNAKDM4EMAPK1TSHR | |
| SCHEMBL6068655 | 0.83 | ABL1 (0.31) | LMNAKDM4EMAPK1TSHR | |
| SCHEMBL1803436 | 0.75 | TSHR (0.38) | LMNASMN1; SMN2KDM4EMAPK1S1PR1 | |
| SCHEMBL5427523 | 0.73 | LMNA (0.33) | LMNASMN1; SMN2KDM4EMAPK1TSHR | |
| SCHEMBL5424153 | 0.72 | LMNA (0.35) | LMNASMN1; SMN2KDM4EMAPK1S1PR1 | |
| SCHEMBL6068724 | 0.71 | TDP1 (0.33) | LMNAALDH1A1 | |
| SCHEMBL6068728 | 0.70 | GAA (0.41) | LMNASMN1; SMN2KDM4ES1PR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |