Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068547 | 0.88 | LMNA (0.31) | LMNAKDM4EMAPK1TSHR | |
| SCHEMBL6068685 | 0.88 | KMO (0.36) | LMNAKDM4E | |
| SCHEMBL6068734 | 0.85 | KMO (0.31) | KDM4E | |
| SCHEMBL6068949 | 0.83 | LMNA (0.34) | LMNAKDM4EMAPK1TSHR | |
| SCHEMBL6068684 | 0.79 | LMNA (0.36) | ABL1BCRLMNAKDM4EMAPK1 | |
| SCHEMBL6068926 | 0.75 | — | — | |
| SCHEMBL6068921 | 0.75 | MAPT (0.33) | — | |
| SCHEMBL6068718 | 0.75 | KMO (0.36) | LMNAKDM4E | |
| SCHEMBL6068760 | 0.75 | — | — | |
| SCHEMBL1803436 | 0.74 | TSHR (0.38) | ABL1BCRLMNAKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |
| US-20040088802-A1 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040088802-A1 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | CBR3, CBR1, CYB5R3 | ABL1 3322/4885BCR 2541/4885LMNA 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.