Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509328 | 0.70 | DAO (0.42) | DAONISCH | |
| SCHEMBL7909006 | 0.67 | DAO (0.45) | DAONISCH | |
| SCHEMBL9509316 | 0.67 | DAO (0.42) | DAONISCH | |
| SCHEMBL2069021 | 0.65 | NISCH (0.39) | DAONISCHLTA4H | |
| SCHEMBL6069296 | 0.65 | NISCH (0.39) | DAONISCHLTA4H | |
| SCHEMBL2071541 | 0.65 | NISCH (0.39) | DAONISCHLTA4H | |
| SCHEMBL9509321 | 0.64 | DAO (0.42) | DAONISCH | |
| SCHEMBL24193236 | 0.62 | DAO (0.44) | DAO | |
| SCHEMBL18365855 | 0.61 | ABCG2 (0.50) | NISCHLTA4H | |
| SCHEMBL4524534 | 0.60 | IMPDH2 (0.41) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109234-B2 | Benzoxathiepine derivatives and their use as medicines | PIERRE FABRE MEDICAMENT (FR) | 2006-09-19 | — | — | US | disclosed |
| EP-1370547-B1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PF MEDICAMENT (FR) | 2004-09-15 | — | — | EP | disclosed |
| US-20040127552-A1 | Benzoaxathiepin derivatives and their use as medicines | PIERRE FABRE MEDICAMENT (FR) | 2004-07-01 | — | — | US | disclosed |
| EP-1370547-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002081464-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127552-A1 | Benzoaxathiepin derivatives and their use as medicines | CYP4A11, CYP3A4, CYP4F11 | DAO 288/4885NISCH 1540/4885LTA4H 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.