Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29959911 | 0.81 | ITGB2 (0.41) | LTB4RLTB4R2HTR2AABCG2ITGB2 | |
| SCHEMBL768353 | 0.81 | ITGB2 (0.41) | LTB4RLTB4R2HTR2AABCG2ITGB2 | |
| SCHEMBL7534538 | 0.81 | MAOA (0.31) | MAOAMAOB | |
| SCHEMBL3516397 | 0.80 | LTB4R (0.40) | LTB4RLTB4R2DRD2DRD3CYP19A1 | |
| SCHEMBL29961242 | 0.78 | ITGB2 (0.39) | LTB4RLTB4R2ITGB2ICAM1ITGAL | |
| SCHEMBL11528526 | 0.74 | LTB4R (0.50) | LTB4RLTB4R2DRD2DRD3LTA4H | |
| SCHEMBL24115366 | 0.72 | PSMB5 (0.41) | LTB4RLTB4R2DRD2DRD3HTR2A | |
| SCHEMBL300098 | 0.69 | NOTUM (0.32) | HTR2A | |
| SCHEMBL4607686 | 0.69 | CHRNB4 (0.36) | HTR2AMAOAMAOB | |
| SCHEMBL5541762 | 0.68 | LTB4R (0.47) | LTB4RLTB4R2DRD2DRD3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118265700-A | Substituted naphthyridinone derivative, pharmaceutical composition and application thereof | 上海海雁医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |
| WO-2023083210-A1 | SUBSTITUTED NAPHTHYRIDINONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-05-19 | — | — | WO | disclosed |
| WO-2023083210-A1 | SUBSTITUTED NAPHTHYRIDINONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-05-19 | — | — | WO | disclosed |
| EP-3344604-A1 | CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-11 | — | — | EP | disclosed |
| EP-2997021-B1 | NEW SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | CENTREXION THERAPEUTICS CORP (US) | 2017-12-20 | — | — | EP | disclosed |
| WO-2017036404-A1 | CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-03-09 | — | — | WO | disclosed |
| US-20090325830-A1 | LUBRICATING COMPOSITIONS WITH IMPROVED OXIDATION RESISTANCE CONTAINING A DISPERSANT AND AN ANTIOXIDANT | SCHNUR ERIC R | 2009-12-31 | — | — | US | disclosed |
| EP-1200540-A4 | MINERAL GEAR OILS AND TRANSMISSION FLUIDS | LUBRIZOL CORP (US) | 2008-09-03 | — | — | EP | disclosed |
| US-6962895-B2 | Lubricating compositions | THE LUBRIZOL CORPORATION (US) | 2005-11-08 | — | — | US | disclosed |
| EP-0786511-B1 | Lubricating compositions | LUBRIZOL CORP (US) | 2005-06-15 | — | — | EP | disclosed |
| US-5622923-A | HAVING IMPROVED ANTIWEAR, EXTREME PRESSURE, ANTIOXIDANT, RUST INHIBITOR PROPERTIES | THE LUBRIZOL CORPORATION (US) | 1997-04-22 | — | — | US | disclosed |
| EP-0748862-A2 | Lubricating compositions, functional fluids and greases containing thiophosphorus esters or their salts with an oxyalkylene group, and methods of using the same | The Lubrizol Corporation (an Ohio corporation) (US) | 1996-12-18 | — | — | EP | disclosed |
| EP-0684298-A2 | Compositions for extending seal life, and lubricants and functional fluids containing the same | The Lubrizol Corporation (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5464548-A | Lubricants, functional fluid and grease compositions containing sulfite or sulfate overbased metal salts and methods of using the same | THE LUBRIZOL CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0678569-A2 | Lubricating compositions with improved oxidation resistance containing a dispersant and an antioxidant | THE LUBRIZOL CORPORATION (US) | 1995-10-25 | — | — | EP | disclosed |
| US-5368758-A | Lubricants, greases and aqueous fluids containing additives derived from dimercaptothiadiazoles | THE LUBRIZOL CORPORATION (US) | 1994-11-29 | — | — | US | disclosed |
| EP-0604232-A1 | Lubricants, functional fluid and grease compositions containing sulfite or sulfate overbased metal salts | The Lubrizol Corporation (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5318712-A | Reacted with A,B-unsaturated ester; antiwear, antioxidant | THE LUBRIZOL CORPORATION (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0593263-A1 | Lubricants, greases, aqueous fluids and concentrates containing additives derived from dimercaptothiadiazoles | The Lubrizol Corporation (US) | 1994-04-20 | — | — | EP | disclosed |
| EP-0592956-A1 | Lubricants, greases and aqueous fluids containing additives derived from dimercaptothiadiazoles | The Lubrizol Corporation (US) | 1994-04-20 | — | — | EP | disclosed |