Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069384 | 0.86 | IDO1 (0.46) | ALDH1A1GAATDP1MAPTMAPK1 | |
| SCHEMBL6069318 | 0.83 | ALDH1A1 (0.37) | CYP19A1ALDH1A1GAATSHRCYP3A4 | |
| SCHEMBL6069604 | 0.81 | GAA (0.47) | CYP19A1ALDH1A1GAATSHRCYP3A4 | |
| SCHEMBL4528900 | 0.77 | CYP3A4 (0.65) | CYP19A1ALDH1A1GAATSHRCYP3A4 | |
| SCHEMBL10702996 | 0.77 | CYP3A4 (0.48) | CYP19A1ALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL27945532 | 0.76 | IDO1 (0.44) | CYP19A1ALDH1A1GAATSHRCYP3A4 | |
| SCHEMBL8142830 | 0.75 | ALDH1A1 (0.85) | CYP19A1ALDH1A1GAATSHRCYP3A4 | |
| SCHEMBL31457288 | 0.75 | ALDH1A1 (0.85) | CYP19A1ALDH1A1GAATSHRCYP3A4 | |
| 4,4'-Methylenedianiline SCHEMBL11059440 | 0.75 | ALDH1A1 (0.85) | CYP19A1ALDH1A1GAATSHRCYP3A4 | |
| SCHEMBL6069500 | 0.75 | ALDH1A1 (0.46) | ALDH1A1GAATSHRCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074243-B2 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-11 | — | — | US | claimed |
| US-7074243-B2 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20030182735-A1 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030182735-A1 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | KRT18, VIM, KPNB1 | CYP19A1 3876/4885ALDH1A1 601/4885GAA 2544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.