Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692979 | 0.82 | NPC1 (0.45) | KITFLT3HDAC1HDAC2 | |
| SCHEMBL5692954 | 0.82 | HPGD (0.45) | KITFLT3FFAR1KLK1KLK5 | |
| SCHEMBL8522825 | 0.81 | TDP1 (0.43) | KLK1KLK5MEN1TP53GAA | |
| SCHEMBL5692901 | 0.80 | ALDH1A1 (0.47) | MEN1TP53GAAMAPTKMT2A | |
| SCHEMBL11693812 | 0.80 | HDAC1 (0.53) | DHFRHDAC1HDAC2TP53GAA | |
| SCHEMBL5693080 | 0.79 | L3MBTL1 (0.49) | GAAMAPTHTTPTPN1PTPN11 | |
| SCHEMBL6738073 | 0.78 | MAPT (0.42) | KITFLT3DHFRKLK1KLK5 | |
| SCHEMBL15348276 | 0.78 | HDAC1 (0.49) | FFAR1DHFRHDAC1HDAC2PTPN1 | |
| SCHEMBL6069202 | 0.78 | PTGDR2 (0.45) | HDAC1MEN1GAAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL6069400 | 0.77 | PTGDR2 (0.44) | KITFLT3HDAC1MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074243-B2 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20030182735-A1 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030182735-A1 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | KRT18, VIM, KPNB1 | KIT 1359/4885FLT3 4307/4885FFAR1 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.