Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 8/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819884 | 0.82 | MAOB (0.48) | HRH3MAOBMAOAPDK2ALOX5 | |
| SCHEMBL6069671 | 0.79 | MAOB (0.45) | HRH3MAOBMAOAPDK2ALOX5 | |
| SCHEMBL539890 | 0.74 | LIPE (0.54) | HRH3MAOBMAOALIPEALOX5 | |
| SCHEMBL29953350 | 0.74 | LIPE (0.68) | HRH3MAOBMAOALIPEALOX5 | |
| SCHEMBL5433420 | 0.74 | LIPE (0.68) | HRH3MAOBMAOALIPEALOX5 | |
| SCHEMBL29950569 | 0.74 | LIPE (0.54) | HRH3MAOBMAOALIPEALOX5 | |
| SCHEMBL29825561 | 0.73 | LIPE (0.53) | HRH3MAOBLIPEALOX5HIF1A | |
| SCHEMBL29954101 | 0.73 | LIPE (0.53) | HRH3MAOBLIPEALOX5HIF1A | |
| SCHEMBL1711426 | 0.73 | LIPE (0.53) | HRH3MAOBLIPEALOX5HIF1A | |
| SCHEMBL18550296 | 0.73 | LIPE (0.53) | HRH3MAOBLIPEALOX5HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067416-A1 | CHEMICAL PROCESSES AND INTERMEDIATES | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |