Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14390809 | 0.89 | ACE (0.42) | ACEALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL26452827 | 0.84 | NPSR1 (0.36) | ALDH1A1NPSR1TSHRPOLBFAAH | |
| SCHEMBL22122404 | 0.81 | RAB9A (0.41) | ALDH1A1NPSR1TSHRPOLBFAAH | |
| SCHEMBL2059432 | 0.81 | RAB9A (0.41) | ALDH1A1NPSR1TSHRPOLBFAAH | |
| SCHEMBL938190 | 0.81 | ACE (0.33) | ACEALDH1A1MEN1KMT2ACSNK2A2 | |
| SCHEMBL9012497 | 0.78 | NPSR1 (0.33) | ALDH1A1NPSR1POLBFAAHNAAA | |
| SCHEMBL367449 | 0.77 | — | — | |
| SCHEMBL29237864 | 0.77 | TOP2A (0.36) | ALDH1A1MEN1KMT2ANPSR1TSHR | |
| SCHEMBL17234427 | 0.77 | ACE (0.31) | ACEALDH1A1 | |
| SCHEMBL18528387 | 0.77 | ACE (0.31) | ACEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074930-B2 | Amine salts of an integrin receptor antagonist | MERCK & CO., INC (US) | 2006-07-11 | — | — | US | disclosed |
| US-6916810-B2 | αν integrin receptor antagonists | MERCK & CO., INC. (US) | 2005-07-12 | — | — | US | disclosed |
| US-20040249158-A1 | Amine salts of an integrin receptor antagonist | MERCK & CO., INC. | 2004-12-09 | — | — | US | disclosed |
| US-20040192670-A1 | Alpha v integrin receptor antagonists | MERCK & CO., INC. | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192670-A1 | Alpha v integrin receptor antagonists | ITGAV, ITGA5, ITGB5 | ACE 4067/4885ALDH1A1 2630/4885MEN1 1580/4885 |
| US-20040249158-A1 | Amine salts of an integrin receptor antagonist | ITGB3, ITGA1, ITGAL | ACE 4271/4885ALDH1A1 1465/4885MEN1 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.