Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenyl Ethanedioat SCHEMBL43364 | 0.82 | TDP1 (0.54) | L3MBTL1ATMELANETDP1MAPT | |
| SCHEMBL82142 | 0.82 | ELANE (0.67) | L3MBTL1ATMELANETDP1MAPT | |
| SCHEMBL11771781 | 0.82 | ELANE (0.67) | L3MBTL1ATMELANETDP1MAPT | |
| Diphenyl Ethanedioat SCHEMBL27942895 | 0.81 | ELANE (0.53) | L3MBTL1ATMELANETDP1MAPT | |
| Diphenyl Ethanedioat SCHEMBL27328178 | 0.80 | TDP1 (0.52) | L3MBTL1ATMELANETDP1MAPT | |
| Diphenyl Ethanedioat SCHEMBL10797780 | 0.78 | TDP1 (0.50) | L3MBTL1ATMELANETDP1MAPT | |
| SCHEMBL5605891 | 0.77 | ALDH1A1 (0.47) | L3MBTL1ATMELANETDP1MAPT | |
| SCHEMBL8117712 | 0.76 | L3MBTL1 (0.47) | L3MBTL1ATMELANETDP1MAPT | |
| SCHEMBL20999892 | 0.76 | MEN1 (0.51) | L3MBTL1ATMELANETDP1MAPT | |
| SCHEMBL15843599 | 0.76 | L3MBTL1 (0.44) | L3MBTL1ATMELANETDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060116400-A1 | Oxazolidinone and/or isoxazoline derivatives as antibacterial agents | ASTRAZENECA AB (SE) | 2006-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116400-A1 | Oxazolidinone and/or isoxazoline derivatives as antibacterial agents | NR0B2, NR0B1, HRH2 | L3MBTL1 3367/4885ATM 4763/4885ELANE 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.