Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.69 |
| ▸ | CFTR | P13569 | 2/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30342070 | 1.00 | ALDH1A1 (0.69) | ALDH1A1HSD17B10CFTRCA1CA2 | |
| SCHEMBL8892028 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CFTRCA1CA2 | |
| SCHEMBL2993964 | 0.89 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CFTRCA1CA2 | |
| SCHEMBL14589543 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CFTRCA1CA2 | |
| SCHEMBL30216752 | 0.89 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CFTRCA1CA2 | |
| SCHEMBL14828744 | 0.89 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CFTRCA1CA2 | |
| SCHEMBL6312035 | 0.88 | CA12 (0.61) | ALDH1A1HSD17B10CFTRCA1CA2 | |
| SCHEMBL6995362 | 0.87 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CFTRCA1CA2 | |
| SCHEMBL1666445 | 0.86 | CA1 (0.64) | ALDH1A1HSD17B10CFTRCA1CA2 | |
| SCHEMBL8547750 | 0.83 | MAPT (0.59) | ALDH1A1HSD17B10CFTRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499531-B | Method for preparing dimethyl aminophthalate | 扬州工业职业技术学院 | 2023-04-07 | — | — | CN | claimed |
| CN-109970568-B | Synthesis process of 3-amino dimethyl phthalate | 扬州工业职业技术学院 | 2022-09-02 | — | — | CN | claimed |
| CN-216172207-U | Hydrogenation reaction kettle for preparing 3-amino-dimethyl phthalate | 山东友帮生化科技有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-110746400-A | Androgen receptor targeted fluorescent probe and preparation method thereof | 郑州大学 | 2020-02-04 | — | — | CN | claimed |
| CN-110483304-A | A kind of preparation method of 3- aminophthalic acid dimethyl ester | YANGZHOU POLYTECHNIC INST | 2019-11-22 | — | — | CN | claimed |
| CN-109970568-A | A kind of green synthesis process of 3- aminophthalic acid dimethyl ester | 扬州工业职业技术学院 | 2019-07-05 | — | — | CN | claimed |
| US-10106550-B2 | Aza-phenalene-3-ketone derivative, preparation method thereof, and its application as PARP inhibitor | SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) | 2018-10-23 | — | — | US | claimed |
| US-20180134722-A1 | AZA-PHENALENE-3-KETONE DERIVATIVE, PREPARATION METHOD THEREOF, AND ITS APPLICATION AS PARP INHIBITOR | SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) | 2018-05-17 | — | — | US | claimed |
| EP-3305793-A1 | DERIVATIVE OF NITROGEN-DOPED PHENALENE-3-KETONE, PREPARATION METHOD THEREFOR AND APPLICATION OF DERIVATIVE USED AS PARP INHIBITOR | Suzhou Kangrun Pharmaceuticals, Inc. (CN) | 2018-04-11 | — | — | EP | claimed |
| CN-104945406-B | Derivative, its preparation method and its application as PARP inhibitor of that non-ketone of alkene 3 of azepine | 苏州康润医药有限公司 | 2017-10-10 | — | — | CN | claimed |
| CN-106631844-A | Preparation method of dimethyl 3-aminophthalate | 山东友帮生化科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-104945406-A | Aza-phenalene-3-ketone derivative, preparation method thereof and application of aza-phenalene-3-ketone derivative as PARP inhibitor | SUZHOU KANGRUN PHARMACEUTICALS INC | 2015-09-30 | — | — | CN | claimed |
| WO-1997047589-A1 | AMINOPHTHALIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-18 | — | — | WO | claimed |
| CN-120040355-A | Synthesis process and application of luminol monosodium salt precursor for chemiluminescent substrate liquid | 浙江鑫科医疗科技有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-119753869-A | Shape memory prestress anchor net material and preparation method thereof | 中煤科工开采研究院有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-116368131-B | Novel Smad3 protein degradation agent and application thereof | 和径医药科技（上海）有限公司 | 2024-09-20 | — | — | CN | disclosed |
| EP-0471756-A1 | SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF. | STERLING WINTHROP INC (US) | 1992-02-26 | — | — | EP | disclosed |
| EP-0101330-B1 | 2-QUINOLONE DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1988-08-24 | — | — | EP | disclosed |
| US-4526894-A | Antiinflammatory agents | NIPPON SHINYAKU CO. LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0101330-A2 | 2-Quinolone derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1984-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134722-A1 | AZA-PHENALENE-3-KETONE DERIVATIVE, PREPARATION METHOD THEREOF, AND ITS APPLICATION AS PARP INHIBITOR | PARP1, PARP11, PARP3 | ALDH1A1 812/4885HSD17B10 583/4885CFTR 4629/4885 |
| US-10106550-B2 | Aza-phenalene-3-ketone derivative, preparation method thereof, and its application as PARP inhibitor | PARP1, PARP11, PARP3 | ALDH1A1 812/4885HSD17B10 583/4885CFTR 4629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.