SCHEMBL1666445

SCHEMBL1666445

COC(=O)c1cccc(C(=O)OC)c1C(=O)OC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.64
CA2 P00918 2/20 0.64
CA9 Q16790 2/20 0.64
CA12 O43570 1/20 0.64
CA7 P43166 1/20 0.64
CA14 Q9ULX7 1/20 0.64
TSHR P16473 3/20 0.59
LMNA P02545 2/20 0.59
ALDH1A1 P00352 3/20 0.57
CFTR P13569 1/20 0.57
HSD17B10 Q99714 1/20 0.57
KDM4E B2RXH2 2/20 0.55
POLB P06746 1/20 0.55
ATM Q13315 1/20 0.55
KMT2A Q03164 3/20 0.50
MAPT P10636 2/20 0.50
CA5A P35218 1/20 0.50
ALOX15 P16050 1/20 0.50
PTPRC P08575 1/20 0.49
SLC6A3 Q01959 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815483 0.94 CA1 (0.57) CA1CA2CA9CA12CA7
SCHEMBL8669428 0.92 CA1 (0.55) CA1CA2CA9CA12CA7
SCHEMBL3576571 0.91 CA1 (0.59) CA1CA2CA9CA12CA7
SCHEMBL6598415 0.87 CA1 (0.55) CA1CA2CA9CA12CA7
SCHEMBL773429 0.87 CA1 (0.55) CA1CA2CA9CA12CA7
SCHEMBL29453452 0.87 CA1 (0.80) CA1CA2CA9CA12CA7
SCHEMBL157121 0.87 CA1 (0.80) CA1CA2CA9CA12CA7
SCHEMBL11296630 0.87 TSHR (0.63) CA1CA2CA9CA12CA7
SCHEMBL8669430 0.86 TSHR (0.55) CA1CA2CA9CA12CA7
SCHEMBL28769090 0.86 CA1 (0.59) CA1CA2CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3917976-B1 METHOD FOR PRODUCING POLYDIENES WITH REDUCED COLD FLOW BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2026-04-15 EP claimed
US-12091474-B2 Method for producing polydienes with reduced cold flow BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2024-09-17 US claimed
CN-114639552-A Electrode material for enhancing capacitive energy by utilizing sunlight irradiation and preparation method thereof 东北大学 2022-06-17 CN claimed
US-20220106421-A1 Method For Producing Polydienes With Reduced Cold Flow BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2022-04-07 US claimed
EP-3917976-A1 METHOD FOR PRODUCING POLYDIENES WITH REDUCED COLD FLOW Bridgestone Americas Tire Operations, LLC (US) 2021-12-08 EP claimed
CN-113412286-A Process for preparing polydienes having reduced cold flow properties 普利司通美国轮胎运营有限责任公司 2021-09-17 CN claimed
WO-2020160000-A1 METHOD FOR PRODUCING POLYDIENES WITH REDUCED COLD FLOW FIRESTONE POLYMERS, LLC (US) 2020-08-06 WO claimed
US-10689489-B2 Polyimide-based block copolymer and polyimide-based film comprising the same LG CHEM LTD. (KR) 2020-06-23 US claimed
EP-3917976-B1 METHOD FOR PRODUCING POLYDIENES WITH REDUCED COLD FLOW BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2026-04-15 EP disclosed
US-12410274-B2 Anionic dispersion polymerization process to make random copolymer rubber BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-20250092071-A1 PROCESS FOR PREPARING ISOCYANATOORGANOSILANES WACKER CHEMIE AG (DE) 2025-03-20 US disclosed
EP-4486315-A1 COMPOSITIONS FOR PREVENTING AND TREATING INFECTION COMPRISING AN ARTIFICIAL SWEETENER Brunel University London (GB) 2025-01-08 EP disclosed
US-12091474-B2 Method for producing polydienes with reduced cold flow BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2024-09-17 US disclosed
US-20240158561-A1 ANIONIC DISPERSION POLYMERIZATION PROCESS TO MAKE RANDOM COPOLYMER RUBBER BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2024-05-16 US disclosed
EP-1412082-A1 METHOD FOR HYDROGENATING ORGANIC COMPOUNDS BY MEANS OF RU/SIO2 CATALYSTS BASF Aktiengesellschaft (DE) 2004-04-28 EP disclosed
EP-1314714-A2 Method for hydrogenating benzene polycarboxylic acids or derivatives thereof by using a catalyst containing macropores BASF AKTIENGESELLSCHAFT (DE) 2003-05-28 EP disclosed
EP-1042273-B1 METHOD FOR HYDROGENATING BENZENE POLYCARBOXYLIC ACIDS OR DERIVATIVES THEREOF BY USING A CATALYST CONTAINING MACROPORES BASF AG (DE) 2003-05-07 EP disclosed
WO-2002100536-A1 METHOD FOR HYDROGENATING ORGANIC COMPOUNDS BY MEANS OF RU/SIO2 CATALYSTS BASF AKTIENGESELLSCHAFT (DE) 2002-12-19 WO disclosed
EP-1042273-A1 METHOD FOR HYDROGENATING BENZENE POLYCARBOXYLIC ACIDS OR DERIVATIVES THEREOF BY USING A CATALYST CONTAINING MACROPORES BASF AKTIENGESELLSCHAFT (DE) 2000-10-11 EP disclosed
WO-1999032427-A1 METHOD FOR HYDROGENATING BENZENE POLYCARBOXYLIC ACIDS OR DERIVATIVES THEREOF BY USING A CATALYST CONTAINING MACROPORES BASF AKTIENGESELLSCHAFT (DE) 1999-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250092071-A1 PROCESS FOR PREPARING ISOCYANATOORGANOSILANES ADH1C, SCLY, MPST CA1 539/4885CA2 618/4885CA9 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.