Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6071924 | 1.00 | CYP11B1 (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL28365787 | 0.80 | KDM4E (0.40) | — | |
| SCHEMBL23703963 | 0.78 | LMNA (0.38) | CYP11B1CYP11B2 | |
| SCHEMBL4389878 | 0.78 | CYP11B1 (0.36) | CYP11B1CYP11B2 | |
| SCHEMBL4389881 | 0.78 | CYP11B1 (0.36) | CYP11B1CYP11B2 | |
| SCHEMBL10414515 | 0.77 | TBXAS1 (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL8370307 | 0.77 | TBXAS1 (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL23704247 | 0.77 | CYP11B1 (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL314908 | 0.76 | CYP11B1 (0.40) | CYP11B1CYP11B2 | |
| SCHEMBL27638465 | 0.73 | CYP11B1 (0.43) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264460-A1 | 3-Cyanoquinoline inhibitors of Tpl2 kinase and methods of making and using the same | WYETH (US) | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264460-A1 | 3-Cyanoquinoline inhibitors of Tpl2 kinase and methods of making and using the same | TNNI3K, CSNK1A1L, CDKL1 | CYP11B1 3326/4885CYP11B2 2931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.