Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 10/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 10/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821606 | 0.91 | KMT2A (0.56) | UBE2MDCUN1D1TP53LMNASMN1; SMN2 | |
| SCHEMBL5821603 | 0.91 | KMT2A (0.56) | UBE2MDCUN1D1TP53LMNASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL2575609 | 0.82 | KMT2A (0.55) | UBE2MDCUN1D1TP53LMNASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6071640 | 0.80 | SLC18A3 (0.64) | SMN1; SMN2ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL6071908 | 0.73 | SLC18A3 (0.54) | SMN1; SMN2ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL6072181 | 0.73 | SLC18A3 (0.56) | LMNAKMT2AMEN1GAA | |
| Trifluoroacetic Acid SCHEMBL6072071 | 0.72 | SLC18A3 (0.62) | MAPK1 | |
| SCHEMBL21392777 | 0.69 | UBE2M (0.82) | UBE2MDCUN1D1TP53LMNASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6071622 | 0.69 | ALDH1A1 (0.44) | LMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7931954 | 0.69 | UBE2M (0.70) | UBE2MDCUN1D1TP53LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | ACKR3, CCR5, CXCR2 | UBE2M 4863/4885DCUN1D1 3343/4885TP53 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.