Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072408 | 0.91 | SMN1; SMN2 (0.48) | LMNAMAPTPOLBGAAMAPK1 | |
| SCHEMBL6072612 | 0.88 | NOTUM (0.53) | LMNAMAPTTP53NOTUM | |
| SCHEMBL6072386 | 0.86 | NOTUM (0.51) | LMNAMAPTTP53NOTUM | |
| SCHEMBL6072035 | 0.86 | NOTUM (0.51) | LMNAMAPTGAATP53NOTUM | |
| SCHEMBL6072351 | 0.83 | SMN1; SMN2 (0.47) | LMNAMAPTPOLBTP53 | |
| SCHEMBL6072321 | 0.83 | NOTUM (0.60) | MAPTNOTUM | |
| SCHEMBL6072370 | 0.83 | NOTUM (0.47) | LMNAMAPTGAATP53NOTUM | |
| SCHEMBL6072032 | 0.82 | NOTUM (0.54) | MAPTNOTUMALDH1A1 | |
| SCHEMBL6072249 | 0.82 | HRH3 (0.48) | LMNAPOLBTP53NOTUM | |
| SCHEMBL6072522 | 0.81 | NOTUM (0.60) | MAPTNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | ADAMS JERRY L | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | CHKB, MAP3K20, MAP3K6 | LMNA 2570/4885MAPT 2965/4885POLB 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.