Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072163 | 0.92 | KDR (0.47) | KDRMAPK14SMN1; SMN2NPC1TP53 | |
| SCHEMBL6072363 | 0.86 | LMNA (0.53) | NOTUMMAPTTP53LMNA | |
| SCHEMBL6072321 | 0.85 | NOTUM (0.60) | NOTUMSYKMAPTTRIM24 | |
| SCHEMBL6072032 | 0.85 | NOTUM (0.54) | NOTUMKDRSYKMAPTSMN1; SMN2 | |
| SCHEMBL6072408 | 0.84 | SMN1; SMN2 (0.48) | NOTUMMAPTSMN1; SMN2TP53LMNA | |
| SCHEMBL6072612 | 0.84 | NOTUM (0.53) | NOTUMMAPTTP53TRIM24LMNA | |
| SCHEMBL6072522 | 0.83 | NOTUM (0.60) | NOTUMSYKMAPTTRIM24 | |
| SCHEMBL6072035 | 0.82 | NOTUM (0.51) | NOTUMKDRMAPTTP53TRIM24 | |
| SCHEMBL6071927 | 0.81 | KDR (0.52) | KDRMAPK14NFKB1NR2C2NFKB2 | |
| SCHEMBL6072483 | 0.80 | KDR (0.61) | KDRMAPK14SYKSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | ADAMS JERRY L | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | CHKB, MAP3K20, MAP3K6 | NOTUM 672/4885KDR 2025/4885MAPK14 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.