Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072151 | 0.92 | RAF1 (0.44) | NOTUMRAF1KDR | |
| SCHEMBL6072612 | 0.87 | NOTUM (0.53) | NOTUMTRIM24RAF1MAPT | |
| SCHEMBL6072522 | 0.86 | NOTUM (0.60) | NOTUMTRIM24CYP11B1CYP11B2SYK | |
| SCHEMBL6072321 | 0.86 | NOTUM (0.60) | NOTUMTRIM24CYP11B1CYP11B2SYK | |
| SCHEMBL6072035 | 0.85 | NOTUM (0.51) | NOTUMTRIM24ALDH1A1KDRMAPT | |
| SCHEMBL6072386 | 0.85 | NOTUM (0.51) | NOTUMTRIM24RAB9ASMN1; SMN2SYK | |
| SCHEMBL6072363 | 0.82 | LMNA (0.53) | NOTUMALDH1A1MAPT | |
| SCHEMBL6072370 | 0.82 | NOTUM (0.47) | NOTUMTRIM24SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6072408 | 0.81 | SMN1; SMN2 (0.48) | NOTUMSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6071927 | 0.81 | KDR (0.52) | RAF1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | ADAMS JERRY L | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | CHKB, MAP3K20, MAP3K6 | NOTUM 672/4885TRIM24 4579/4885RAF1 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.