SCHEMBL607237

SCHEMBL607237

O=C(O)c1ccc(Br)c(Br)c1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
ALDH1A1 P00352 2/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 3/20 0.41
AKR1C3 P42330 3/20 0.40
AKR1C4 P17516 2/20 0.40
AKR1C2 P52895 2/20 0.40
AKR1C1 Q04828 2/20 0.40
SELL P14151 1/20 0.39
SELP P16109 1/20 0.39
WDR5 P61964 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
ERN1 O75460 1/20 0.39
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29045172 0.98 CYP1A2 (0.46) CYP1A2ALDH1A1ALOX15TSHRAKR1C3
SCHEMBL1372033 0.89 CYP1A2 (0.58) CYP1A2ALDH1A1ALOX15TSHRAKR1C3
SCHEMBL29981799 0.89 CYP1A2 (0.58) CYP1A2ALDH1A1ALOX15TSHRAKR1C3
Ether SCHEMBL9736112 0.84 HSD17B10 (0.45) CYP1A2ALDH1A1TSHRKDM4ELCK
SCHEMBL3940987 0.83 TSHR (0.47) CYP1A2ALDH1A1TSHRKDM4ECASP1
SCHEMBL11741404 0.82 CYP1A2 (0.50) CYP1A2ALDH1A1ALOX15TSHRAKR1C3
SCHEMBL78614 0.81 SELL (0.52) CYP1A2ALDH1A1TSHRAKR1C3AKR1C4
SCHEMBL140751 0.81 CYP1A2 (0.44) CYP1A2ALDH1A1ALOX15TSHRAKR1C3
SCHEMBL6508228 0.81 AKR1C3 (0.47) CYP1A2ALDH1A1ALOX15TSHRAKR1C3
SCHEMBL195812 0.81 CYP1A2 (0.44) CYP1A2ALDH1A1ALOX15TSHRAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119253090-A Zn-I2Battery electrolyte and preparation method and application thereof 中国科学院大连化学物理研究所 2025-01-03 CN claimed
CN-110437055-A A kind of preparation method of 2,4,6- tribromo benzoic acid SHANGHAI ALADDIN BIOCHEMICAL TECH CO LTD 2019-11-12 CN claimed
WO-2012168470-A1 METHOD FOR THE DETERMINATION OF THE CONCENTRATION OF VITAMIN B6 IN A SAMPLE BÜHLMANN LABORATORIES AG (CH) 2012-12-13 WO claimed
US-20090203877-A1 X-RAY-DENSE CONJUGATE EBERHARD-KARLS-UNIVERSITAET TUEBINGEN UNIVERSITAETSKLINKUM 2009-08-13 US claimed
EP-2046392-A2 RADIODENSE CONJUGATE Eberhard-Karls-Universität Tübingen Universitätsklinikum (DE) 2009-04-15 EP claimed
WO-2008012102-A2 RADIODENSE CONJUGATE EBERHARD-KARLS-UNIVERSITAET TUEBINGEN UNIVERSITAETSKLINIKUM (DE) 2008-01-31 WO claimed
US-5185471-A Reacting 5-halo-2-nitrobenzotrifluorides with inorganic base to form 1,1*-oxy-Bis(3-trifluoromethyl-4-nitrobenzen using benzoate catalyst OCCIDENTAL CHEMICAL CORPORATION (US) 1993-02-09 US claimed
EP-0365541-B1 PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES BRACCO S.p.A. (IT) 1992-08-12 EP claimed
US-5066823-A Rearrangement reaction, contrast agent for radiology BRACCO INDUSTRIA CHEMICA S.P.A. (IT) 1991-11-19 US claimed
EP-0365541-A1 PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES. BRACCO IND CHIMICA SPA (IT) 1990-05-02 EP claimed
WO-1988009328-A1 PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1988-12-01 WO claimed
CN-119253090-A Zn-I2Battery electrolyte and preparation method and application thereof 中国科学院大连化学物理研究所 2025-01-03 CN disclosed
CN-111589472-B Carboxyl-containing conjugated microporous polymer/TiO 2 Method for preparing composite material 齐齐哈尔大学 2022-11-29 CN disclosed
US-10188910-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
CN-108593633-A A kind of Test paper for quickly detecting saliva uric acid 中山大学 2018-09-28 CN disclosed
WO-1988009328-A1 PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1988-12-01 WO disclosed
EP-0038165-B1 ELECTRO-OPTICAL DEVICE AND ELECTRO-OPTICAL LIGHT CONTROLLING DEVICE ASAHI GLASS COMPANY LTD. (JP) 1984-07-25 EP disclosed
US-4435048-A LARGE AREA OPTICAL DISPLAY ASAHI GLASS COMPANY LTD. (JP) 1984-03-06 US disclosed
EP-0038165-A1 Electro-optical device and electro-optical light controlling device ASAHI GLASS COMPANY LTD. (JP) 1981-10-21 EP disclosed
US-4113939-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1978-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203877-A1 X-RAY-DENSE CONJUGATE FCGR3B, KLK3, XPA CYP1A2 1630/4885ALDH1A1 2704/4885ALOX15 3306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.