Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607237 | 0.84 | CYP1A2 (0.48) | TSHRKDM4EALDH1A1LCKFYN | |
| SCHEMBL29045172 | 0.82 | CYP1A2 (0.46) | TSHRKDM4EALDH1A1LCKFYN | |
| SCHEMBL7550971 | 0.81 | HSD17B10 (0.51) | HSD17B10TSHRKDM4EALDH1A1RAB9A | |
| SCHEMBL29092380 | 0.76 | TSHR (0.55) | HSD17B10TSHRKDM4EALDH1A1KMT2A | |
| SCHEMBL9736115 | 0.76 | TSHR (0.55) | HSD17B10TSHRKDM4EALDH1A1KMT2A | |
| SCHEMBL29981799 | 0.76 | CYP1A2 (0.58) | TSHRKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL1372033 | 0.76 | CYP1A2 (0.58) | TSHRKDM4EALDH1A1HPGDCYP1A2 | |
| Dioxane SCHEMBL8130861 | 0.73 | HSD17B10 (0.44) | HSD17B10TSHRKDM4EPOLBALDH1A1 | |
| Ether SCHEMBL11447771 | 0.73 | ALOX15 (0.37) | KDM4EPOLBALDH1A1RAB9AKMT2A | |
| SCHEMBL6425339 | 0.73 | HSD17B10 (0.38) | HSD17B10TSHRKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365541-B1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES | BRACCO S.p.A. (IT) | 1992-08-12 | — | — | EP | disclosed |
| US-5066823-A | Rearrangement reaction, contrast agent for radiology | BRACCO INDUSTRIA CHEMICA S.P.A. (IT) | 1991-11-19 | — | — | US | disclosed |
| EP-0365541-A1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES. | BRACCO IND CHIMICA SPA (IT) | 1990-05-02 | — | — | EP | disclosed |
| WO-1988009328-A1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1988-12-01 | — | — | WO | disclosed |