Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.84 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607245 | 1.00 | AR (0.84) | ARPGRCYP3A4 | |
| SCHEMBL2450766 | 0.91 | AR (1.00) | AR | |
| SCHEMBL16871452 | 0.91 | AR (1.00) | AR | |
| SCHEMBL29359806 | 0.91 | AR (1.00) | AR | |
| SCHEMBL2689756 | 0.91 | AR (1.00) | AR | |
| SCHEMBL114161 | 0.90 | AR (0.79) | ARPGRCYP3A4 | |
| SCHEMBL114162 | 0.90 | AR (0.79) | ARPGRCYP3A4 | |
| SCHEMBL14252926 | 0.90 | AR (0.85) | ARPGRCYP3A4 | |
| SCHEMBL12706742 | 0.90 | AR (0.85) | AR | |
| SCHEMBL3698441 | 0.90 | AR (1.00) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424853-B1 | NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION, PROCESSES FOR THE PREPARATION AND USES THEREOF | ISTITUTO SCIENT ROMAGNOLO PER LO STUDIO E LA CURA DEI TUMORI I R S T S R L (IT) | 2018-09-19 | — | — | EP | disclosed |
| US-8859599-B2 | Androgen receptor modulating compounds, preparation and uses thereof | CNR—Consiglio Nazionale Delle Ricerche (IT) | 2014-10-14 | — | — | US | disclosed |
| US-8741951-B2 | Non-steroidal compounds for androgen receptor modulation | CNR—Consiglio Nazionale Delle Ricerche (IT) | 2014-06-03 | — | — | US | disclosed |
| US-20120041046-A1 | NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION | CNR - CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2012-02-16 | — | — | US | disclosed |
| EP-2396297-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS, PREPARATION AND USES THEREOF | Consiglio Nazionale Delle Ricerche (IT) | 2011-12-21 | — | — | EP | disclosed |
| US-20110275829-A1 | Androgen receptor modulating compounds, preparation and uses thereof | CNR - CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2011-11-10 | — | — | US | disclosed |
| WO-2010092546-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS, PREPARATION AND USES THEREOF | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275829-A1 | Androgen receptor modulating compounds, preparation and uses thereof | AR, NR5A1, SHBG | AR 1/4885PGR 38/4885CYP3A4 508/4885 |
| US-20120041046-A1 | NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION | NR5A1, AR, SHBG | AR 2/4885PGR 43/4885CYP3A4 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.