Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073149 | 0.90 | PPARG (0.48) | PPARGMEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL6072999 | 0.89 | PPARG (0.47) | PPARGMEN1KMT2ACYP3A4RXRA | |
| SCHEMBL6073124 | 0.88 | PPARG (0.44) | PPARGMEN1KMT2ACYP3A4RXRA | |
| SCHEMBL6073155 | 0.87 | PPARG (0.50) | PPARGMEN1KMT2ACYP3A4RXRA | |
| SCHEMBL6073195 | 0.85 | PPARG (0.44) | PPARGMEN1KMT2ACYP3A4RXRA | |
| SCHEMBL6073133 | 0.83 | PPARG (0.49) | PPARGMEN1KMT2ACYP3A4RXRA | |
| SCHEMBL6073005 | 0.82 | PPARA (0.49) | PPARGMEN1KMT2ACYP3A4RXRA | |
| SCHEMBL6073008 | 0.81 | PPARG (0.47) | PPARGCYP3A4RXRALTA4HSLC2A1 | |
| SCHEMBL6073140 | 0.80 | PPARG (0.43) | PPARGMEN1KMT2ACYP3A4RXRA | |
| SCHEMBL6073085 | 0.80 | LMNA (0.44) | PPARGMEN1KMT2ATDP1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |