SCHEMBL6073085

SCHEMBL6073085

CCOC(=O)CN(Cc1cccc(OCCc2ccc(CC)cn2)c1)C(=O)Oc1ccccc1OC

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
SLC2A1 P11166 6/20 0.44
SLC2A4 P14672 2/20 0.44
SLC2A8 Q9NY64 1/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PPARA Q07869 5/20 0.39
PPARG P37231 2/20 0.39
ALDH1A1 P00352 1/20 0.39
AR P10275 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6073124 0.92 PPARG (0.44) LMNASLC2A1SLC2A4MEN1KMT2A
SCHEMBL6073190 0.91 PPARG (0.41) LMNASLC2A1SLC2A4SLC2A8PPARA
SCHEMBL6073264 0.91 PPARA (0.47) LMNASLC2A1SLC2A4SLC2A8PPARA
SCHEMBL6072990 0.91 SLC2A1 (0.48) LMNASLC2A1SLC2A4SLC2A8PPARA
SCHEMBL6073074 0.91 PPARA (0.46) LMNASLC2A1SLC2A4SLC2A8PPARA
SCHEMBL6073152 0.89 SLC2A1 (0.49) LMNASLC2A1SLC2A4SLC2A8PPARA
SCHEMBL6073210 0.88 PPARG (0.50) LMNASLC2A1SLC2A4PPARAPPARG
SCHEMBL6073162 0.88 PPARA (0.43) LMNASLC2A1SLC2A4SLC2A8PPARA
SCHEMBL6073078 0.86 PPARG (0.45) LMNASLC2A1SLC2A4SLC2A8PPARA
SCHEMBL6073095 0.86 PPARG (0.52) LMNASLC2A1SLC2A4PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006117743-A1 SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO claimed
WO-2006117743-A1 SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed