Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CBX7 | O95931 | 1/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073211 | 0.90 | OPRK1 (0.51) | OPRK1ALDH1A1MAPTTSHRL3MBTL1 | |
| SCHEMBL6073548 | 0.83 | OPRK1 (0.48) | OPRK1ALDH1A1MAPTTSHRL3MBTL1 | |
| SCHEMBL6073175 | 0.83 | PPARA (0.44) | ALDH1A1MAPTTSHRPPARAPPARG | |
| SCHEMBL5428115 | 0.82 | PPARA (0.56) | OPRK1ALDH1A1TSHRSMPD1PPARA | |
| SCHEMBL6073615 | 0.81 | OPRK1 (0.48) | OPRK1ALDH1A1MAPTTSHRL3MBTL1 | |
| SCHEMBL27576382 | 0.81 | L3MBTL1 (0.54) | ALDH1A1TSHRL3MBTL1SMPD1MEN1 | |
| SCHEMBL6073497 | 0.80 | OPRK1 (0.46) | OPRK1ALDH1A1MAPTTSHRL3MBTL1 | |
| SCHEMBL5428793 | 0.80 | PPARA (0.52) | OPRK1ALDH1A1TSHRL3MBTL1PPARA | |
| SCHEMBL6073156 | 0.77 | PPARA (0.44) | PPARAPPARG | |
| SCHEMBL5423669 | 0.77 | PPARA (0.54) | ALDH1A1MAPTSMPD1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |