Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CBX7 | O95931 | 1/20 | 0.41 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.41 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.41 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073548 | 0.93 | OPRK1 (0.48) | OPRK1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6073615 | 0.92 | OPRK1 (0.48) | OPRK1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6073010 | 0.90 | OPRK1 (0.51) | OPRK1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6073497 | 0.90 | OPRK1 (0.46) | OPRK1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6073183 | 0.85 | NPSR1 (0.52) | ALDH1A1TSHRMAPTPPARAPPARG | |
| SCHEMBL14360396 | 0.81 | PPARA (0.44) | OPRK1ALDH1A1TSHRMAPTL3MBTL1 | |
| SCHEMBL6073002 | 0.81 | NPSR1 (0.51) | OPRK1ALDH1A1TSHRMAPTPPARA | |
| SCHEMBL6073520 | 0.79 | NPSR1 (0.49) | ALDH1A1TSHRMAPTPPARAPPARG | |
| SCHEMBL6073165 | 0.79 | NPSR1 (0.49) | ALDH1A1TSHRMAPTPPARAPPARG | |
| SCHEMBL6073297 | 0.77 | NPSR1 (0.47) | ALDH1A1TSHRMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |