Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073251 | 0.90 | CYP1A2 (0.46) | POLBMAPTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL6073134 | 0.87 | CYP1A2 (0.44) | RXFP1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6073126 | 0.85 | POLB (0.47) | POLBRXFP1ALDH1A1KDM4EMAPT | |
| SCHEMBL6073213 | 0.83 | LMNA (0.46) | POLBEIF4EBP1RXFP1ALDH1A1KDM4E | |
| SCHEMBL6073125 | 0.82 | PPARA (0.51) | POLBRXFP1ALDH1A1KDM4EMAPT | |
| SCHEMBL6073209 | 0.80 | PPARA (0.50) | RXFP1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6073497 | 0.78 | OPRK1 (0.46) | FAAHALDH1A1KDM4EMAPT | |
| SCHEMBL6073491 | 0.78 | PPARG (0.53) | — | |
| SCHEMBL6073238 | 0.77 | NPSR1 (0.45) | FAAHALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL6073205 | 0.77 | PPARG (0.55) | POLBRXFP1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |