Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073125 | 0.93 | PPARA (0.51) | LMNAPPARAPPARGPOLBRXFP1 | |
| SCHEMBL6073209 | 0.92 | PPARA (0.50) | LMNAPPARAPPARGRXFP1HPGD | |
| SCHEMBL6073205 | 0.89 | PPARG (0.55) | PPARAPPARGPOLBRXFP1 | |
| SCHEMBL6073251 | 0.85 | CYP1A2 (0.46) | LMNAPPARAPPARGPOLBHPGD | |
| SCHEMBL6073134 | 0.84 | CYP1A2 (0.44) | LMNAPPARAPPARGRXFP1HPGD | |
| SCHEMBL6073234 | 0.84 | GFER (0.44) | PPARAPPARGRXFP1EIF4EBP1HPGD | |
| SCHEMBL6073070 | 0.83 | FAAH (0.41) | LMNAPOLBRXFP1EIF4EBP1HPGD | |
| SCHEMBL6073126 | 0.80 | POLB (0.47) | LMNAPPARAPPARGPOLBRXFP1 | |
| SCHEMBL6073000 | 0.74 | PPARG (0.49) | LMNAPPARAPPARGMAPTMEN1 | |
| SCHEMBL6073031 | 0.74 | PPARA (0.81) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |