Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073238 | 0.91 | NPSR1 (0.45) | KDM4EALDH1A1LMNAGAAHTT | |
| SCHEMBL6073175 | 0.90 | PPARA (0.44) | ALDH1A1LMNAPPARAPPARGTSHR | |
| SCHEMBL6073207 | 0.89 | PPARG (0.39) | PPARAPPARGCYP2C9KCNH2DRD2 | |
| SCHEMBL6073063 | 0.82 | TSHR (0.41) | ALDH1A1LMNAPPARAPPARGTSHR | |
| SCHEMBL6073290 | 0.81 | DRD2 (0.39) | LMNAPPARAPPARGDRD2DRD1 | |
| SCHEMBL6073183 | 0.81 | NPSR1 (0.52) | ALDH1A1LMNAPPARAPPARGTSHR | |
| SCHEMBL6073297 | 0.79 | NPSR1 (0.47) | ALDH1A1LMNAFAAHDRD2DRD1 | |
| SCHEMBL6073165 | 0.77 | NPSR1 (0.49) | ALDH1A1LMNAPPARAPPARGTSHR | |
| SCHEMBL6073002 | 0.77 | NPSR1 (0.51) | KDM4EALDH1A1LMNAPPARAPPARG | |
| SCHEMBL6073497 | 0.77 | OPRK1 (0.46) | KDM4EALDH1A1KMT2AFAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |