Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073290 | 0.92 | DRD2 (0.39) | TSHRCHRM1PPARAPPARGNPSR1 | |
| SCHEMBL6073121 | 0.90 | NPSR1 (0.48) | TSHRPPARAPPARGNPSR1LMNA | |
| SCHEMBL6073175 | 0.90 | PPARA (0.44) | TSHRCHRM1PPARAPPARGNPSR1 | |
| SCHEMBL6073207 | 0.87 | PPARG (0.39) | TSHRCHRM1PPARAPPARGBCHE | |
| SCHEMBL6073462 | 0.83 | NPSR1 (0.45) | TSHRNPSR1LMNAALDH1A1 | |
| SCHEMBL6073092 | 0.82 | KDM4E (0.40) | TSHRPPARAPPARGLMNASMN1; SMN2 | |
| SCHEMBL6073174 | 0.81 | NPSR1 (0.49) | TSHRNPSR1LMNAALDH1A1 | |
| SCHEMBL6073183 | 0.81 | NPSR1 (0.52) | TSHRPPARAPPARGNPSR1LMNA | |
| SCHEMBL6073520 | 0.80 | NPSR1 (0.49) | TSHRPPARAPPARGNPSR1LMNA | |
| SCHEMBL6073165 | 0.79 | NPSR1 (0.49) | TSHRPPARAPPARGNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |