Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 4/20 | 0.37 |
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | MMP3 | P08254 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 4/20 | 0.37 |
| ▸ | MMP7 | P09237 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264590 | 0.91 | KDM1A (0.44) | KDM1ANISCHLTA4HTSHRMMP1 | |
| SCHEMBL571789 | 0.85 | SLC18A3 (0.41) | KDM1ANISCHALDH1A1MAOBMAOA | |
| SCHEMBL9331689 | 0.81 | MAOA (0.50) | KDM1ANISCHALDH1A1MAOBMAOA | |
| SCHEMBL10518245 | 0.77 | MAOA (0.54) | TSHRCHRNB2CHRNA4MAOBMAOA | |
| SCHEMBL1616732 | 0.75 | KDM1A (0.38) | KDM1A | |
| SCHEMBL595524 | 0.75 | HTR3A (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10520604 | 0.75 | TAAR1 (0.39) | KDM1ATSHRKCNH2SMN1; SMN2MAOB | |
| SCHEMBL9375602 | 0.75 | CYP19A1 (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL240623 | 0.75 | ADCY5 (0.38) | NISCH | |
| SCHEMBL10519054 | 0.75 | MAOA (0.56) | LTA4HTSHRALDH1A1LMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006118749-A1 | THIA-TETRAAZAACENAPHTHYLENE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-11-09 | — | — | WO | disclosed |