Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 3/20 | 0.48 |
| ▸ | BRD1 | O95696 | 3/20 | 0.48 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.48 |
| ▸ | BRPF3 | Q9ULD4 | 3/20 | 0.48 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074068 | 0.83 | CES1 (0.61) | ALDH1A1MAPTHTR6RECQLLMNA | |
| SCHEMBL28751618 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTHTR6RECQLLMNA | |
| SCHEMBL376491 | 0.82 | KDM4E (0.59) | TP53POLB | |
| SCHEMBL6074374 | 0.80 | POLB (0.59) | ALDH1A1MAPTHTR6RECQLLMNA | |
| SCHEMBL6074070 | 0.80 | MAPT (0.55) | ALDH1A1MAPTHTR6RECQLDRD3 | |
| SCHEMBL6074493 | 0.80 | KMT2A (0.75) | ALDH1A1MAPTRECQLLMNAKMT2A | |
| SCHEMBL6073863 | 0.79 | GFER (0.77) | ALDH1A1MAPTKDM1ARECQLLMNA | |
| SCHEMBL6074309 | 0.77 | MAPT (0.61) | ALDH1A1MAPTRECQLLMNAKMT2A | |
| SCHEMBL6074894 | 0.77 | KMT2A (0.54) | ALDH1A1MAPTRECQLDRD2DRD3 | |
| SCHEMBL6074981 | 0.76 | CYP3A4 (0.54) | ALDH1A1MAPTHTR6RECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022716-B2 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | WYETH (US) | 2006-04-04 | — | — | US | disclosed |
| US-20030144326-A1 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | WYETH | 2003-07-31 | — | — | US | disclosed |
| US-6525202-B2 | E.g., substituted (4-amino-5-hydroxyphenyl)-oxy-)piperidinyl thiazolidin-2,4-dione; antidiabetic agents; atherosclerosis, gastrointestinal, metabolic disorders, glaucoma, neurogenetic inflammation, ocular hypertension and frequent urination | WYETH | 2003-02-25 | — | — | US | disclosed |
| US-20020028835-A1 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | WYETH | 2002-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144326-A1 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | ADRB1, ADRB3, ADRB2 | ALDH1A1 1091/4885MAPT 565/4885HTR6 451/4885 |
| US-20020028835-A1 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | ADRB1, ADRB3, ADRB2 | ALDH1A1 1091/4885MAPT 565/4885HTR6 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.