Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27480159 | 0.98 | HTT (0.66) | HTTPOLBNOS2MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL27300450 | 0.98 | HTT (0.66) | HTTPOLBNOS2MAPTNPC1 | |
| SCHEMBL27360703 | 0.91 | HTT (0.58) | HTTPOLBNOS2MAPTNPC1 | |
| SCHEMBL8058000 | 0.87 | HTT (0.58) | HTTPOLBNOS2MAPTNPC1 | |
| SCHEMBL30691783 | 0.87 | HTT (0.58) | HTTPOLBNOS2MAPTNPC1 | |
| SCHEMBL20411802 | 0.84 | HTT (0.54) | HTTPOLBMAPTNPC1RAB9A | |
| SCHEMBL20804371 | 0.84 | HTT (0.61) | HTTNPC1MEN1CYP1A2CYP3A4 | |
| SCHEMBL259701 | 0.84 | MAPT (0.65) | HTTNOS2MAPTNPC1RECQL | |
| SCHEMBL29038583 | 0.83 | HTT (0.62) | HTTNOS2MAPTNPC1RAB9A | |
| SCHEMBL28606837 | 0.83 | HTT (0.62) | HTTPOLBMAPTMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111592505-A | Synthesis method of iodine-catalyzed 2-substituted benzoselenazole compound | 衡阳师范学院 | 2020-08-28 | — | — | CN | claimed |
| CN-101484524-B | Method of preparing resin composition for artificial marble chip having high specific gravity and high index of refraction | CHEIL INDUSTRIES INC. (KR) | 2011-12-21 | — | — | CN | claimed |
| CN-101484524-A | Method of preparing resin composition for artificial marble chip having high specific gravity and high index of refraction | CHEIL IND INC (KR) | 2009-07-15 | — | — | CN | claimed |
| CN-1032444-A | Make polyacrylate polymers sulfurized vulcanization process without issue | GOODRICH CO B F (US) | 1989-04-19 | — | — | CN | claimed |
| CN-111592505-A | Synthesis method of iodine-catalyzed 2-substituted benzoselenazole compound | 衡阳师范学院 | 2020-08-28 | — | — | CN | disclosed |
| CN-110923744-A | Method for constructing secondary amine compound through reductive amination reaction of electrochemical aldehyde | 五邑大学 | 2020-03-27 | — | — | CN | disclosed |
| EP-1390340-B1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9067955-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon—carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-06-30 | — | — | US | disclosed |
| CN-102146007-B | Method for preparing secondary amine and tertiary amine | DALIAN CHEMICAL PHYSICS INST | 2013-10-23 | — | — | CN | disclosed |
| CN-101484524-B | Method of preparing resin composition for artificial marble chip having high specific gravity and high index of refraction | CHEIL INDUSTRIES INC. (KR) | 2011-12-21 | — | — | CN | disclosed |
| CN-101484524-A | Method of preparing resin composition for artificial marble chip having high specific gravity and high index of refraction | CHEIL IND INC (KR) | 2009-07-15 | — | — | CN | disclosed |
| US-20060264673-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-11-23 | — | — | US | disclosed |
| US-7115784-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-10-03 | — | — | US | disclosed |
| US-20050215794-A1 | Copper-catalyzed formation of carbon heteroatom and carbon-carbon bonds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-09-29 | — | — | US | disclosed |
| US-6867298-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2005-03-15 | — | — | US | disclosed |
| US-6759554-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-07-06 | — | — | US | disclosed |
| US-20040019216-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-01-29 | — | — | US | disclosed |
| US-20030065187-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-04-03 | — | — | US | disclosed |
| CN-1032444-A | Make polyacrylate polymers sulfurized vulcanization process without issue | GOODRICH CO B F (US) | 1989-04-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264673-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | ADH5, CBR3, ALDH3A1 | HTT 1214/4885POLB 3522/4885NOS2 944/4885 |
| US-20050215794-A1 | Copper-catalyzed formation of carbon heteroatom and carbon-carbon bonds | CBR3, ADH5, IDH1 | HTT 986/4885POLB 3503/4885NOS2 1229/4885 |
| US-20030065187-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | ADH5, CBR3, ALDH3A1 | HTT 1214/4885POLB 3522/4885NOS2 944/4885 |
| US-20040019216-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | ADH5, CBR3, ALDH3A1 | HTT 1214/4885POLB 3522/4885NOS2 944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.